Features
Several missed opportunities of achieving communal harmony
(Continued from Feb. 08)
Although the die had been cast, the next event was a pusillanimous attempt, even the purpose of which was shrouded in doubt and conjecture. This was a tentative legislative step in the form of the District Developments Councils Act of 1980. The legislation was preceded by the appointment of a Presidential Commission, which was presided over by Mr. Victor Tennekoon QC, a former Chief Justice and Attorney General, and comprised a membership of four Sinhalese, three Tamils, and three Muslims.
At the initial stage itself, lack of courage was demonstrated in the reluctance to include in the Terms of Reference any allusion to the ethnic conflict. This gave rise to an irreconcilable difference of opinion among the members as to the nature and scope of their mandate. Hardline opinion within the government precluded direct reference to the ethnic dimension. But some of the members of the Commission, including Professor A. J. Wilson, a close confidant of President J. R. Jayewardene and son-in-law of the leader of the Federal Party, Mr. S. J. V. Chelvanayakam, had secured informal agreement with the President that the government would be well disposed to consideration of broader issues having a bearing on the ethnic conflict, should these be addressed in the contents of the report. This was, however, strongly resisted by the majority of the members who were inclined to adopt a narrow, technical interpretation of the Terms of Reference.
In the end, the report of the majority tended to have an exclusively administrative focus. The thrust of the recommendations had to do with making district administration more receptive to the needs of the people in the 25 administrative districts, and improving the quality of services delivered to them through the instrumentality of District Development Councils. The main levers for effecting this purpose were the Councils themselves and the District Ministers. Elected DDC members, joined by members of Parliament from the district, formed the composition of the Councils. The District Minister, as the principal repository of executive power in the district, had the role of coordinating the functions of all central government institutions operating in the district.
Even from the limited perspective of streamlining the administrative machinery at district level, this proved, across the board, an exercise in futility, even though there were some positive features. Obvious blemishes marred critical aspects of the enacted law, for example, vesting in the President, rather than in the membership of the Council, responsibility for appointment of the District Minister. In any event, the Councils were seriously hamstrung by both pecuniary and institutional constraints. There was no political will to allocate financial resources, and the prevailing culture of patronage inhibited Ministers and officials at the Centre from genuine transfer of authority to the district tier. The impact of the legislation, by and large, was negligible.
The true issues, however, lay elsewhere. The context of the legislation was one in which Tamil formations, such as the Tamil United Liberation Front, were struggling to maintain their moderate postures in an increasingly polarized environment, with pressure from radical elements proving almost irresistible. Two members of the Commission, Prof. A. J. Wilson and Dr. Neelan Tiruchelvam, in their dissenting report, tried to find space, at least interstitially, in a situation where the province could not be identified realistically as the unit of devolved power, to use the district development structure in the North and the East as an intermediate mechanism to allay minority apprehensions and to hold extremism at bay. It was an uphill task, further compounded by two Muslim members of the Commission, in a different dissenting report, expressing the polar opposite view, hostile to ampler devolution on the ground of perceived harm to Muslim interests. Fissures and divisions within the polity were manifested by the resolve of the major Opposition party, the Sri Lanka Freedom Party, to distance itself entirely from the work of the Presidential Commission.
This unpromising backdrop produced a result which was seen largely as a non-event. This paled into insignificance in comparison with a sequence of tragic events which pushed themselves to the centre of the stage. These included the burning of the Jaffna Library during the run-up to the District Development Council elections in the North, and the events of Black July, 1983, which gravely scarred inter-communal relations for a long time. Policymakers at a critical juncture had once again let a limited opportunity slip through their fingers.
ZENITH OF INDIAN INTERVENTION
The next few years typified the high point of Indian intervention. The story of the Thimpu Principles, the IndoSri Lanka Accord, and other connected developments is chronicled in the substantive chapters of this work.
MANGALA MOONESINGHE SELECT COMMITTEE OF PARLIAMENT
In the sunset years of the United National Party administration, yet another attempt was made “to arrive at a political solution to the question involving the devolution of power to the Northern and Eastern Provinces” and to rein in terrorist connected violence. This was the Parliamentary Select Committee on the Ethnic Conflict, appointed in August, 1991. There were several novel features in this endeavour.
First, in contrast with initiatives typically resorted to by the executive arm of government, this was an attempt by the legislature. Consisting of 45 Members of Parliament, drawn from across the political spectrum, this was one of the largest Select Committees appointed by the Parliament of our country. Its chair was Mr. Mangala Moonesinghe, a Member of the Opposition. It deliberated for two years and had 49 meetings. Its outcome was the submission of several reports— the Majority Report, to which the United National Party, the Sri Lanka Freedom Party, the Sri Lanka Muslim Congress, the Communist Party of Sri Lanka and the Lanka Samasamaja Party subscribed, a dissenting report of seven Tamil political parties, and a further dissent by Mr. Dinesh Gunawardena of the Mahajana Eksath Peramuna.
Second, there was a substantial convergence of approach between the two major parties, the Sri Lanka Freedom Party and the United National Party, on the contours of devolution acceptable at the time. Departing from antagonistic attitudes typical of the recent past, there was a measure of agreement about the desirability of a federal constitution and the need for more generous devolution of power.
Third, the Majority Report of the Committee made a detailed proposal which was intended to serve as the foundation of a compromise between two schools of thought— one, stoutly resisting any idea of merger of the Northern and Eastern Provinces, and the other demanding such merger as the indispensable basis of a viable solution. An imaginative via media, although somewhat hazy at the edges, was the concept of the Apex Council which formed the centerpiece of the Majority Report. Formulated in a Concept Paper and further refined in an Option Paper, it adopted as a point of departure two separate Provincial Councils for the North and the East. This dichotomy would characterize the provincial executive as well: each Provincial Council would have an Executive Minister as the head of the Board of Ministers. However, over and above these, the two Provincial Councils together would constitute a Regional Council for the entire North East region.
When the two Provincial Councils met together to discuss matters relating to the region as a whole, they would constitute themselves as the Regional Council. The Regional Council would be headed by a Chief Minister for the entire region, the two Executive Ministers functioning in rotation. The two Provincial Boards of Ministers meeting on matters pertaining to the region would be designated the Regional Board of Ministers. There would be a Regional List and a Provincial List, and legislative functions were to be exercised by the Regional Council for the region with respect to those functions set out in the Regional List. The Provincial List would contain matters such as land, finance, and law and order, and the Regional List would apply to such matters as planning and economic development.
There would be a single Governor for the region, and the rights of minorities would be guaranteed by the Constitution. Legislation passed by the Regional Council would not be operative in the Province until it was approved by the relevant Provincial Council.
Although presenting several features of interest as a pragmatic mediating mechanism, the proposal did not enjoy a sufficiently broad support base to be capable of implementation. In any case, there was no indication of commitment by the Presidency and the Government. Indeed, during the pendency of the Mangala Moonesinghe Committee, the Government of President Ranasinghe Premadasa passed incompatible legislation. The effect of the Transfer of Powers (Divisional Secretaries) Act of 1992 was to vest in divisional secretaries powers which had previously been exercised by the Government Agents. This was, arguably, an insidious attempt to claw back to the Centre powers exercised as a matter of practice at the periphery, thus undermining the direction and thrust of the Mangala Moonesinghe Committee proposals.
KUMARATUNGA’S ACCESSION TO POWER AND THE JAFFNA TALKS
The election of Chandrika Bandaranaike Kumaratunga, first as Prime Minister and then as President in 1994, marked a significant event in the politics of the Island.
Kumaratunga’s identification as the dove of peace, evoking emotive responses especially in the North of the country, was a powerful element of the imagery at a time when a war weary mood had gripped the nation. This was effectively captured in Kumaratunga’s message to the country soon after her victory at the Parliamentary election: “The verdict of our people in the recent elections leaves me in no doubt of the depth and intensity of their desire and commitment to peace. This must be, however, peace with honour, for both parties to the conflict, for it to be strong and durable.”
Unfortunately, this pervasive feeling of euphoria did not last long. In retrospect, the reasons for this are worth reflection.
There is no doubt that one of the priorities of the new government was peace negotiations with the LTTE. There were four rounds of talks in Jaffna over a period of six months. The first letter from Kumaratunga to Prabhakaran was written on September 2, 1994, and the initial round of talks took place on October 13 and 14. The final letter from Prabhakaran, signifying the irretrievable breakdown of the negotiating process, was dated April 18, 1995.
Failure of this phase of the talks is attributable to a number of causes:
I The structure of the process discouraged systematic progress. Although there were face-to-face meetings between the two delegations at regular intervals, the critical component of the process consisted of an exchange of letters over the entire period. Some of these letters were exchanged between Kumaratunga and Prabhakaran, but, for the most part, the signatories were Kusumsiri Balapatabendi, at the time Secretary to the Prime Minister, or Anuruddha Ratwatte, Deputy Minister of Defence, on the Government side, and S. P. Tamilselvan, Head of the Political Wing, on behalf of the LTTE. This epistolary medium of communication was profoundly unsatisfactory: it provided no scope for a meeting of minds to discuss complex issues in depth and with sincerity.
II The level of the government delegation gave rise to deep disappointment on the part of the LTTE. Kumaratunga nominated four representatives—Mr. K. Balapatabendi, Secretary to the Prime Minister; Mr. Lionel Fernando, Secretary to the Ministry of Information, Tourism and Aviation; Mr. R. Asirwatham, Chairman of the Bank of Ceylon; and Mr. N. L. Gooneratne, Chairman of Design Consortium Limited. Three other members were inducted into the delegation as the talks continued. These were the Right Reverend Bishop Kenneth Fernando, Dr. Jayadeva Uyangoda, and Mr. C. Abeysekara. The LTTE complained bitterly that “the nominees were personal emissaries or confidants of the President, who lacked professional experience in peace negotiations, nor did they possess any political authority to make decisions”. In correspondence with the status of the government delegation, the LTTE nominated as their representatives Mr. K. Karikalan, Deputy Head of the Political Section; Mr. S. Elamparuthy, Political Organizer of the Jaffna District; Mr. A. Ravi, Head of the Department of Economic Research and Development; and Mr. S. Dominic, Head of the Department of Public Administration. It seemed to the LTTE that the composition of the government delegation was indicative of a lack of seriousness of purpose.
III The LTTE, as part of the measures to engender an enabling environment, pressed for a ceasefire. The government steadfastly resisted this demand on the basis that it would be appropriate not at the very outset, as a precondition for commencement of talks, but when reasonably substantial progress had been made. The maximum concession which the government was minded to make was a “cessation of hostilities” which they qualitatively distinguished from a ceasefire. Modalities of the truce, embodied in the document which came into effect on January 8, 1995, were brief and sketchy. They supplied an insufficient framework for dealing with the volatile situations which inevitably developed. Among these were the mobility of armed LTTE guerrillas and the movement of Sea Tigers. There were recurring complaints that the government showed no interest in taking steps to convert the cessation of hostilities into a ceasefire.
IV There was, throughout the process, an all-too-evident trust deficit. The government entertained serious doubts about the LTTE’s commitment to the search for a durable political solution. Reciprocally, the LTTE believed that government initiatives were motivated by the quest for partisan political gain. They gave vent to this sentiment in the observation that “the government was very subtle and sophisticated in the art of propaganda. Already an effective campaign had been launched internationally.”23 The LTTE felt that, uppermost in the government’s mind, was the development of a pre-emptive strategy to impute blame to the LTTE, in the eyes of the international community, should the talks fail. The depth of mutual suspicion and distrust could well have been mitigated by availability of foreign facilitation, for which there was no provision at that stage.
V Serious incidents, potentially destructive of the process, occurred from the very outset. On 12 November, 1994, to coincide with Kumaratunga’s assumption of office as President, the LTTE declared a unilateral cessation of hostilities for seven days. In an army ambush in the Nedunkerni area, a senior LTTE cadre was killed and decapitated. Acrimonious correspondence followed, with regard to return of the severed head. In an incident on the waters around Mannar, the Sea Tigers attacked and destroyed a Sri Lankan frigate, causing the deaths of 24 Navy personnel.
In this background, the cessation of hostilities agreement, once signed, to be effective, necessarily required a mutually acceptable monitoring mechanism. This was entirely lacking. The International Committee of the Red Cross (ICRC), invited by the government to take on this role, declined on the ground of want of military expertise needed for successful implementation of the mandate.
The government then set up peace committees in six areas of the North East and invited four foreign delegates from three Western countries—Auden Holm and John Gabrielson from Norway, Lt. Col. Paul Henry Horsting from Holland, and Maj. Gen. C. Milner from Canada— to function as chair of these committees. Less than an optimal arrangement, this suffered a setback at the start, with bitter recriminations by the LTTE over the government’s failure to arrange a meeting between them and the foreign monitors prior to the latter being dispatched to Trincomalee and Batticaloa to commence their work. The process was grievously impaired by the absence of even the semblance of an effective authority to perform an indispensable function.
VI From beginning to end, a debilitating factor was excessive informality hardly commensurate with the nature of the issues involved. The government sought the LTTE’s concurrence to use, as an intermediary, a retired French diplomat, who had served as ambassador in Haiti and was willing to offer his services on the firm understanding that the government of France was in no way privy to his assignment. The LTTE saw no merit in this proposal because of its entirely unofficial character, and also because of the special relationship of the suggested intermediary with one party. As the talks floundered on the verge of collapse, and one final attempt to salvage them was decided upon, the person selected to spearhead the effort was a senior member of the Christian clergy, scarcely equipped with credentials for so daunting a task.
VII The structure of the talks called for a sharp focus on “existential” issues in the North and East as a preliminary to discussion of political issues. This part of the negotiation, however, was mired in rancour and suspicion throughout its course. Lifting of the economic embargo gave rise to incessant disputes which were never resolved. The border post at Thandikulam exemplified
this situation. Restrictions on fishing, opening of the Sengupidy road and its bearing on Pooneryn camp, and the movement of armed LTTE cadres in the East, were among the other issues which proved incapable of resolution. In the absence of any coherent strategy, the talks did not move forward.
The important question is whether these shortcomings were seriously considered, and a productive effort made to overcome them, in the Norwegian-facilitated negotiation which occupied the next phase. This is considered in the chapters which follow.
(Excerpted from The Sri Lanka Peace Process: An Inside View by GL Peiris)
Features
‘A remarkable time capsule’: The enchanting history of Oxford University’s 750-year-old medieval library
Predating the Aztec Empire, Merton College Library in Oxford has been used by everyone from celebrated 14th-Century mathematicians to JRR Tolkien. In an exclusive interview with the BBC for its 750th birthday, its librarian describes what makes it so special.
At Merton College in Oxford, there is an antique chest. In the Middle Ages, three key-holders had to be summoned to reveal the riches within. But this treasure wasn’t gold or jewels. It was books.
Such strict security may sound overly cautious for mere parchment. But in an era before the printing press, books were a valuable commodity. They could take months to produce, as the entire text had to be painstakingly written out by hand. So, just as universities solicit cash from their alumni today, Merton College insisted its 13th-Century fellows donated books.
“There’s no single definition of a library” – Prof Teresa Webber
The Archbishop of Canterbury issued a decree in 1276 introducing this requirement, which marked the beginning of the library at Merton College. It has been running continuously ever since. To put that length of time in context, Merton’s library predates the Aztec Empire. Its unbroken history stretches from before the Black Death to beyond the Covid-19 pandemic. And its users have encompassed everyone from famous 14th Century mathematicians to Lord of the Rings author JRR Tolkien.
This month marks the library’s 750th anniversary. It’s a major milestone. But Merton’s extraordinary lifespan has been recognised since the Victoria era, when it was routinely described as the oldest library in England.
In the 20th Century, writers like Rudyard Kipling and John Buchan referenced it in works of historical fiction, bolstering its reputation as a particularly venerable library. As the cultural recognition of “the famous Merton Library” grew, claims about its longevity became exaggerated. Some overzealous Oxonians even declared it the oldest library in the world.
The origins of the historic library
Historians today are more careful about making such bold declarations. “It’s a complicated question,” says Prof Teresa Webber from the University of Cambridge. “There’s no single definition of a library. And there were all sorts of stages in the development of what we think of today as a library.”

The origins of the library at Merton are certainly different from how we think of such institutions now. There was no librarian and there were no shelves for browsing. “There was a system of loaning and returning books from the chest,” Merton’s librarian, Dr Julia Walworth tells the BBC. “It would have been a formal thing. Rather than just saying, ‘Oh, go rummage and find the books you need,’ the whole community would come together to open the chest.”
“Horizontal shelves were installed for placing books upright. Merton is the first recorded use in Britain of this method of storing books” – Dr Julia Walworth
Merton’s collection started evolving into a modern library quite quickly. Just a few years after the Archbishop’s decree, several books were stored outside the chest for the first time. They were chained to a table in the college, making them available at any time. According to Walworth, this innovation “anticipates the modern distinction between loan and reference library collections”.
Merton’s book treasury moved closer to becoming a modern library in the 1370s, when a purpose-built room was constructed to house the growing collection. It was here that Merton introduced a vital improvement in book storage. “Horizontal shelves were installed for placing books upright,” Walworth says. “Merton is the first recorded use in Britain of this method of storing books.”
Curiously, Merton’s books were shelved with their spines inwards and their titles inked on the paper facing out. This was due to the continued use of chains, which were clipped on the fore-edge of each book’s cover. “The fellows were aware that chained books had a better chance of survival than books that went out on loan,” Walworth explains.

Today, just a few volumes in the library are chained – purely for display purposes. And the remaining books are now placed in the modern fashion with their spines out. But otherwise, the medieval room remains a remarkable time capsule of the library’s history. Near the entrance, visitors can even see the 13th-Century chest, which Walworth believes is the original. During term time, the historic library room is still used by students. And this ongoing use is a major factor in the superlatives that are often applied to the age of Merton’s library. “It’s hard to think of an earlier library room that’s been in continuous use,” Webber says.
Claims about Merton’s longevity first gained traction in the Victorian era, as it became more of a tourist destination. Visitors would marvel at its stained-glass windows, as well as rare books like its 15th-Century edition of The Canterbury Tales. “It’s one of the earliest books printed in England,” Walworth explains. “What’s unique about Merton’s copy is the hand-illuminated borders.” Among those who visited the library was American writer Ralph Waldo Emerson, who mentioned it in his 1856 travelogue English Traits. In 1884, a young Beatrix Potter visited, describing the library’s “beautiful oak roof” and “ancient, dusty smell” in her diary.
By this time, books and magazines were increasingly describing the library in record-breaking terms. An 1878 guide to Oxford called Merton’s library “the most ancient now in England”. The 1885 edition of the Encyclopaedia Britannica described it as “the oldest existing library in England”. Gradually, these claims were inflated. A 1928 article in The Times recounted an event held by the Oxford Preservation Trust in which it was declared “the oldest library in the world”.

This growing perception of Merton’s longevity was even referenced in F Scott Fitzgerald’s classic novel The Great Gatsby. In the book, the multi-millionaire title character fills his mansion with imitations of history’s most prestigious rooms. So, it’s only natural that his books live in a recreation he refers to as “the Merton College Library”. As Walworth puts it, “Merton’s library had become a byword for the ‘best’ ancient library” by that time. She even points out that Fitzgerald’s fictional scenario had roots in reality. “The dining clubs at Princeton University have historical imitation rooms. One of them is based on the Merton College Library.”
But today, Walworth rebukes any suggestion that Merton’s library is the world’s oldest. She prefers to describe it with several qualifiers, calling it “one of the oldest still-functioning academic libraries in Europe”. That more measured description recognises that not all historic libraries can be categorised in the same bucket – monastic libraries functioned very differently from private subscription libraries, for instance. But it also acknowledges ancient institutions around the globe. “It’s not that people weren’t aware of other parts of the world in the past,” Walworth says. “But there was a tendency for people to think of their own world as having primacy. Our outlook tends to be more global now, quite rightly.”
The debate over the world’s oldest library
Among these global institutions, there are several candidates for the contested title of world’s oldest library. When the Al-Qarawiyyin library in Morocco underwent a major restoration in 2016, it was described by several media outlets as “the oldest library in the world”. But Guinness World Records cites Saint Catherine’s Monastery in Egypt as the oldest continuously operating library.

In both cases, it’s difficult to establish an exact starting date. For the Al-Qarawiyyin library, some scholars have cast doubt on the library’s claims of Ninth-Century origins, saying the “story has much myth about it”. In the case of Saint Catherine’s Monastery, the building was constructed in the Sixth Century. But ancient writings suggest that the library’s collections could date from two centuries earlier. “It depends how you count it,” Walworth says. “When are you going to start the timeline? What is the beginning of a library?”
However, Prof Richard Gameson from Durham University tells the BBC that the library at Saint Catherine’s Monastery “is probably the one with the longest continuous history”. But he caveats this by adding that “the nature of the ‘library’, how it was used and how it was understood changed over time”. So, any claim to be “the oldest” needs to be accompanied by an appropriate explanation of what a library is. Finding a single definition that allows for one conclusive record-holder seems a near-impossible task.
“You can think of the oldest library as the oldest coherent collection of books that stayed together,” says Webber. “Or you can think of it in terms of the survival of the physical space. Or you could ask, ‘What’s the oldest space and collection of books which has been there continuously?'”
She offers the Dunhuang Library Cave in China as an example. This secret chamber was filled with manuscripts and sealed sometime around the 11th Century. It was only opened again after its rediscovery in 1900. “But the books were still in continuous storage there,” Webber says.

Finding a common definition of a library will only become more challenging now, as digital institutions offer physical spaces that do not even contain any books. “The definition of what a library is has always needed to be a capacious one,” says Webber. “The introduction of new technology is simply a continuation of that. But I don’t think the library as a physical space will disappear.”
Walworth is similarly optimistic, as she embarks on a project to digitise Merton’s manuscripts. “People will be able to access them anywhere. But I think they will still want to come and see the library and understand how people used books in the past.”
Reflecting on the 750-year span of Merton’s library, this digital phase seems like just another step in a long evolution. Just as the books moved from the Archbishop’s chest to chained desks to horizontal shelves, now they will enter the virtual realm. “I suppose that’s why I now find it less useful to talk about libraries as ‘the oldest’,” Walworth says. “For me, the story is not about how long a library has been running. It’s more about the sense of community.”
She points out that the tradition of donating books introduced by the Archbishop of Canterbury in 1276 persists to this day. “What started when he laid down those injunctions was the idea of a common collection built by the people. So, it’s just remarkable that for 750 years people have maintained this connection with an institution and its books.”
Perhaps that proves that books really are the most durable treasure – whether they are handwritten on parchment and sealed in an antique chest or distributed as pixels in the cybernetic ether.
[BBC]
Features
Discovery of molecular structure of primary genetic material of life
World DNA Day falls on 25 April:
On 25 April 1953, Watson and Crick published an article, in the acclaimed journal “Nature” titled “Molecular structure of nucleic acids: A structure for deoxyribonucleic acid”.
The one-page article largely based on theoretical arguments and the previous work of Rosalind Franklin who examined DNA using X-rays, changed the world forever by explaining how genetic information is copied and transmitted.
Everyone concerned with promoting science in the country should be aware of the story behind the discovery of DNA and tell it to their children and students and remind the policymakers.
The world commemorates the transformative event on 25th April every year. An example vividly illustrates how intense curiosity and imagination, rather than mere indulgence in technologies, leads to groundbreaking discoveries.
DNA Day is also intended to celebrate the completion of the Human Genome Project in 2003. Genome means the entire set of genetic information characterising an organism.
Heredity and inheritance
Heredity is the cause of transferring traits from parents to their offspring. The closely related word “inheritance “refers to the specific nature of the transmitted trait. For example, we say intelligence is hereditary in their family and he inherited his father’s intelligence.
The resemblance of progeny to parentage was common knowledge, taken for granted and considered a blending of maternal and paternal traits. Philosophers of antiquity proposed several theories to explain the inheritance of parental traits by the offspring. Hippocrates believed the essence of all body parts of the parents are incorporated into the male and female germinal essence and therefore the offspring display characteristics as a proportionate blend. Aristotle offered a different explanation. He argued that the active principle is in the male seminal fluid and the mother’s blood provided the original body material. The inaccuracy of these theories was apparent. Sometimes children possess qualities akin to grandparents rather than parents. Fathers or mothers of humans and animals, deformed by accidents or disease, gave birth to normal children- a clear proof that the acquired characters are not inherited. Children of a blue-eyed mother and a brown-eyed father have either blue or brown eyes but not a blend of blue and brown.
Two golden sayings in our culture, “Arae gathi nare” and “Jammeta wada lokuei purrudha” (“Hereditary characters persist” and “Habits overtake heredity “), agree more with modern genetics, than the views of Hippocrates and Aristotle.
Gregor Mendal’s groundbreaking experiment
The Austrian mathematician cum botanist, Gregor Mendel was the first to conduct a systematic investigation to understand the cause of heredity. Being unconvinced of the traditional explanations, he carried out a series of experiments lasting eight years to determine how the traits (plant height, seed color, flower color etc.) of pea plants are transmitted from generation to generation. When Mendel cross pollinated tall and short plants, he found that the progeny was entirely tall. However, when first generation tall plants were allowed to self-pollinate, the missing short trait reappeared at a statistically significant probability of 25 percent. Mendel’s work provided an unequivocal proof that traits do not blend but exist as unique entities, manifested from generation to generation following a predictable mathematical pattern.
Mendel’s finding remained unrecognized for more than 30 years. His ideas were too far ahead of time and biologists were shy of mathematics. In the early 1900s several European botanists arrived at the same conclusion based on independent experiments. With the advancement of microscopy, a great deal of information about plant and animal cells was gathered. A key finding was the presence of colored bodies in the cell nucleus named chromosomes, seen separating during cell division, leading to the hypothesis that Mendel’s genetic units (genes) should be physical entities present in the chromosomes.
Chemists and biologists wondered what the genetic material in chromosomes made off. Is it a protein, carbohydrate or a lipid? Most biological materials are constituted of these substances.
Discovery of DNA
Great discoveries are made by unusual people. The Swiss Friedrich Miescher belonged to a clan of reputed physicians. Following family tradition, he qualified as a doctor but did not engage in profitable practice of medicine. He decided to do research to understand the foundations of life. In search for new biological substances, he experimented with pus deposited in bandages and extracted a substance rich in phosphates but very different from proteins. The new substance called “nuclein” was indeed DNA. Later, the German biochemist Albrecht Kossel following the Miescher’s work, showed that DNA contains four crucial compounds, adenine (A), cytosine (C), guanine (G) and thymine (T), known as nucleotide bases.
Avery – MacLeod – McCarthy Experiment
The flu pandemic of 1918 killed an estimated 50 million people worldwide due to the pneumonia that followed the viral infection. Pneumonia was caused by the virulent bacterium Streptococcus pneumoniae. The British bacteriologist, Frederick Griffith attempting to find a vaccine for pneumonia, worked with two strains of Streptococcus pneumoniae, one virulent causing pneumonia in mice, and the other avirulent to them. He found that neither the virulent strain denatured by heating nor the live avirulent strain injected into mice caused the disease, whereas a mixture of the denatured virulent strain and the live avirulent strain was deadly to mice just as the virulent one. He concluded that some chemical compound present in the virulent strain – a transforming principle – has changed the avirulent strain to the virulent strain.
In 1944, Oswald Avery, Colin MacLeod and Maclyn McCarty working at the Rockefeller University, United States, continued the work of Frederick Griffith to identify the transferring principle and found that it is not protein as widely believed, but deoxyribonucleic acid (DNA). Their result pointed to the conclusion that DNA is the carrier of genetic information.
A book by a physicist that triggered a transformation in biology
The insights of brilliant brains engaged in fundamental inquiry have opened the way for major scientific discoveries and technological innovations. In 1944, the Austrian theoretical physicist Erwin Schrodinger, one of the founders of quantum mechanics, published a book titled “What is life? The physical aspect of the living cell “. The American biologist Maurice Wilkins said he was so inspired by Schrodinger’s book and after reading it, he decided to switch from ornithology to genetics. While physicist Maurice was influenced to take up biology. Francis Crick was a physicist working on magnetic mines for the British Admiralty during the war. After reading “What is life” he thought a physicist could find treasures in biology and joined the Cavendish Laboratory in Cambridge to pursue a Ph.D.
Structure of the DNA molecule
When DNA was shown to be the molecular entity that encodes genetic information, chemists rushed to determine its structure.
The pattern formed when X-rays passing through a material cast an image on a screen, provides information about its molecular structure. In 1938, the English physicist William Astbury examined DNA using x-rays and concluded that the molecule has a helical structure. Having heard a group in the United Kingdom was attempting to unearth the structure of DNA, the American theoretical chemist, Linus Pauling, adopted Astbury’s data and proposed a model for the structure of DNA, publishing the results in the journal “Nature” in January 1953.
There was an obscure but remarkably talented person, Rosalind Franklin, pursuing x-ray diffraction studies on DNA at King’s College London. After a painstaking effort, she obtained accurate x-ray diffraction images of DNA. Her colleague, Maurice Wilkins, working in the same laboratory, passed the images to Francis Crick and James Watson at Cavendish Laboratory.
Crick and Watson were more insightful and theoretical in their approach to elucidating the structure of DNA. They, inspired by Erwin Schrodinger’s hypothesis, that the entity accounting for heredity should be an aperiodic molecular entity in cells, arrived at the double helix model, showing that Linus Pauling’s model was erroneous. The Crick – Watson model explained how DNA stores information and replicates during cell division. Their assertions were subsequently confirmed rigorously by experimentation. Crick, Watson and Wilkins received the Nobel Prize for Physiology and Medicine in 1962.
The work following the Crick – Watson model, firmly established that the DNA is a polymer string constituted of two strands made of a sugar- phosphate backbone, connected to each other by linkage nucleotide bases A, T, G, C. The base A links base T and G to C. When one strand is defined by the arrangement of bases, the complementary strand is defined. The arrangement bases store information analogously to a four-letter alphabet. Each individual in a species has a unique sequence of arrangement base pairs. The variation within the species is generally a fraction of a percent.
The Watson-Crick model also explained how the DNA molecule replicates. The two strands unwind and separate, and two complementary strands are inserted. The detailed dynamics of the replication process are not fully understood.
‘DNA is a cookbook’
DNA functions like a multiple – volume cookbook, written in a four-letter alphabet. The volumes are kept in a rack in the kitchen. The rack is the nucleus and volumes on it are the chromosomes, and the cell is the kitchen. A paragraph giving a recipe is a gene. Enzymes act as chefs, who read recipes and give instructions to cell machinery to prepare the dishes, which are proteins. The system is so complex; a complete macroscopic analogy would be impossible.
The significance of the Crick- Watson work
Until Charles Darwin proposed the idea of evolution, biology lacked a theoretical foundation. Darwin hypothesized, when organisms reproduce, the progeny inherit parental characters, but there are variations. The variants, though similar to the parents, have some new or altered characters. If these characters, originating from mutations or cross – breeding are favorable for survival in the environment, they dominate in the population, inheriting advantageous traits. Thus, random generation – to – generation, advancements of living organisms, become possible – a way of improving the design of things in a production process without a designer. Living systems store information and progeny retrieve them, when required. A bird hatched from an egg when matured, knows how to fly.
The discovery of DNA and understanding how it stores genetic information, replicates and mutates explained Darwinian evolution. A mutation is a change in the ordering of base pairs, accidentally during replication or due to external chemical or physical causes. In sexual reproduction, the offspring gets nearly half of its DNA from each parent. Consequently, the offspring does not have DNA identical to one parent. It mixes up DNA in the species. However, mutations generate new genes, driving evolution. Sexual reproduction and mutation acting in concert introduced the diversity of life on earth we see today.
Once science becomes explanatory and predictive, it opens the way for innovations. Theories of mechanics and electromagnetism formulated in the late 19th and early 20th centuries brought forth modern engineering, transforming it from an empirical craft to a scientific technological discipline. Before the discovery of DNA structure and its function, biological innovations were largely empirical. Today we have genetic engineering – genes in organisms can be manipulated. The goal of more advanced genetic engineering, referred to as synthetic biology, aims to induce major genetic changes to organisms by incorporating several genes to alter biochemical, physiological and anatomical functions. Gene technology is rapidly transforming medicine, agriculture and biotechnology. Cures have been found for diseases formerly branded incurable.
How did DNA come into existence
Life is believed to have originated in prebiotic oceans enriched with carbon and nitrogenous substances. How did DNA originate there? Today, chemists can synthesize DNA in minutes, via selective procedures, only humans can do with their knowledge. Even in a vast ocean containing trillions of times more molecular ingredients than in a test tube, a molecule as complex as DNA is most unlikely to be created by random events during the largest possible time scales of the universe. A plausible scenario would be DNA evolving from simpler self-replicating molecules such as RNA (a single strand of DNA) precursors. Unlike RNA, DNA is highly stable and good stability is necessary for the evolution of advanced forms of life.
Epigenetics
Earlier we pointed out there are two golden sayings in our culture: “Arae gathi nare” and “Jammeta wada lokuei purudha (“Hereditary characters persist” and “Habits overtake heredity “). The first is a consequence of our genetic predisposition determined by DNA and explicit genes. However, the character of an individual is also influenced by the physical, social and cultural environment. Although completely non-genetic, our children frequently follow habits we indulge in. Again, the behavior of an individual is also influenced by the physical, social and cultural environment.
The environmental factors also trigger or silence genes. The study of this important genetic effect, which does not alter the sequence of base pairs, is referred to as epigenetics. Epigenetic effects could be deleterious or beneficial. Sometimes, chronic stress causes disease, including cancer. Research suggests engagement in creative and imaginative activities, and establishes favorable epigenetic changes in the brain. Inheritance is dictated mainly by the arrangement of base pairs in DNA. Epigenetic changes involve chemical changes in DNA without altering the sequence. These alterations are erasable but allow transmission to subsequent generations.
Conclusion: World DNA day message to lawmakers
The discovery of the structure of DNA stands as one of the most significant scientific discoveries in human history. It is a lesson to all those involved in research and education, telling how great discoveries originated. It is intense curiosity, imagination and preparation rather than mere indulgence in technologies that clear the path for discovery and innovation. A society that advocates policies conducive to discoveries, also develops new technologies that follow. If we just borrow technologies from places where they originated, hoping for quick economic returns, the effort would be a gross failure. Students, determined to be the best judging from exam performance, engage in professional disciplines and perform exceptionally. Why are we short of discoveries and innovations in those disciplines? Will our lawmakers ever realize the issue? They need to wonder why we are weak in science and poor in innovation. Right policies can even reverse adverse epigenetic attributes propagating in a society!
By Prof. Kirthi Tennakone
ktenna@yahoo.co.uk
National Institute of Fundamental Studies
Features
Death of the Sperm Whale
REVIEWED BY Prof. Rajiva Wijesinha
Earlier this year, I sent her most recent book by an old friend, Kamala Wijeratne. Death of the Sperm Whale is her first book of poetry in four years, though in between she has published fiction, two books though both of them too were slim volumes. I am full of admiration for her in that she keeps going, the last of the poets whom I helped to a wider readership in the eighties, when I championed Sri Lankan writing in English, something hardly any academic was prepared to do in those conservative days.
Kamala’s subjects are those she has explored in the past, but the use of the plural indicates that her range is expansive. She dwells much on nature, but she deals also with political issues, and engages in social criticism. There are several poems about Gaza, the multiple horrors occurring there having clearly affected her deeply. She repeatedly draws attention to the slaughter of children, the infants sent by God only to be taken back. And she deals with the destruction of the life of a doctor, after his healing, a theme that has kept recurring in the ghastly world which is subject to the whims of the incredibly nasty Netanyahu.
The title poem is about a whale destroyed by ingesting plastic, a tragedy to which we all contribute, though those who ‘loll on the beach, their senses dulled by the burgers they eat’ could not care less. More immediate is the simple account of a friend whose infant had died in hospital, when they diagnosed pneumonia too late.
Contrasting with these urgent statements are Kamala’s gentle perceptions, as when she writes of her son supporting her as she walks, while she thinks back to the days she supported him; of a marigold growing in a crack in a shrine, offering obeisance with its golden flowers to the Noble One; of birds investigating her dining room and deciding not to build there, the male lingering ‘confused and irritated’ but eventually following the female through the window for ‘She was mistress after all.’
She is deeply interested in the passing of time, and its impact on our perceptions. The first poem in the book is called ‘First Poem of 2024’ when she ‘heard the weeping of the dying year’, and went on to meditate on how we have categorised the passing of time, while the universe moves on regardless.
She welcomes the return of the Avichchiya, the Indian Pitta, a bird that has figured previously in her poetry, after six months, but this time she spares a thought for his case against the peacock, which stole his plumes.
There are two personal poems, one about a former student who turned her back on her when she had achieved success, the other about being nominated for a literary award, but not getting it after the excitement of attending the Awards Ceremony. Swallowing her disappointment, she congratulates the winner, noting that she will not go into ecstasies the next time she is nominated.
Paraphrase cannot do justice to Kamala Wijeratne’s gentle touch, which has expanded its reach over the years. So,A I will end by quoting from her tribute to Punyakante Wijenaike, another of the distinguished ladies whose work I promoted, the one before the last to leave us. The tribute ends, recalling her most impressive work Giraya,
Like the nutcracker
That makes a clean cut
You cut the human psyche
To reveal its darkest depths
by Kamala Wijeratne
-
News5 days agoRs 13 bn NDB fraud: Int’l forensic audit ordered
-
Opinion6 days agoShutting roof top solar panels – a crime
-
News3 days agoLanka faces crisis of conscience over fate of animals: Call for compassion, law reform, and ethical responsibility
-
News2 days agoNo cyber hack: Fintech expert exposes shocking legacy flaws that led to $2.5 million theft
-
News7 days agoFrom Nuwara Eliya to Dubai: Isha Holdings markets Agri products abroad
-
News2 days agoWhistleblowers ask Treasury Chief to resign over theft of USD 2.5 mn
-
News6 days agoChurch calls for Deputy Defence Minister’s removal, establishment of Independent Prosecutor’s Office
-
Life style7 days agoAfter dark in Sri Lanka: Tiny wild cats step into the spotlight

