Features
Proposed Penal Code amendmentand threat of promotion of sexual abuse of children – IV
by Kalyananda Tiranagama
Executive Director
Lawyers for Human Rights and Development
(The third part of this article appeared in The Island of 13 June 2023)
Joining the discussion, Freedom People’s Congress MP Prof. Charitha Herath has said that they would support decriminalization of same-sex relations, if and when the Bill is presented to Parliament.
‘‘We must engage with two domains to achieve the desired results. One is the political domain and the other is the cultural domain. We can change old fashioned political and cultural establishments through constant engagement. ‘’
‘’The technical approach alone will not usher in a meaningful change. That is why I highlight the importance of cultural discussions, as well, to overcome the existing barriers. Sometimes, I feel that these cultural platforms are forgotten by the younger generation,’’ Prof. Herath explained.
Minister Jeevan Thondaman countered the argument that culture was a barrier in achieving non-discrimination for the LGBTQ community in SL. He said ‘’ There is more than enough evidence from ancient history that same sex relations existed and they were very much embraced many, many centuries ago.’’ Thondaman pledged support to legislative reforms decriminalizing same-sex relations.
(E) Existing Penal Code provisions compared with Proposed Amendments
S. 365 of the original Penal Code: ‘’ Whoever voluntarily has carnal intercourse against the order of nature with any man, woman, or animal shall be punished with imprisonment of either description for a term which may extend to 10 years and shall also be liable to fine.’’
In the Penal Code there is no definition as to what is meant by carnal intercourse against the order of nature. According to Indian cases, acts of anal sex and oral sex were considered as carnal intercourse against the order of nature. The Police had no idea as to what is meant by it. Only where there was a complaint of a person having anal or vaginal sex with an animal, like a cow, goat or a bitch, they acted on it. This happened very, very seldom and this provision remained almost unenforced.
However, with the promotion of tourism in the 1980s, many incidents of foreign tourists having anal sex with male children were reported. The Police used to produce the suspects in courts for committing an offence not under this Section but under S. 365A of the Penal Code, carrying a much less penalty.
By 1995 Amendments, S. 365 was amended by adding a clause making it explicitly applicable to punish sexual abusers of children.
1995 Amendment of S. 365 of the Penal Code –
‘’ Whoever voluntarily has carnal intercourse against the order of nature with any man, woman, or animal shall be punished with imprisonment of either description for a term which may extend to 10 years and shall also be punished with fine and where the offence is committed by a person over 18 years of age in respect of a person under 16 years of age, the offender shall be punished with rigorous imprisonment for a term not less than 10 years and not exceeding 20 years and with fine and shall also be ordered to pay compensation of an amount determined by court to the person in respect of whom the offence was committed for injuries caused to such person.’’
The new Bill proposes to repeal S. 365 and substitute it with the following section:
‘’Whoever voluntarily has carnal intercourse against the order of nature with an animal, shall be punished with imprisonment of either description for a term which may extend to 10 years and shall also liable to fine.’’
Under the proposed Bill, anal or oral sex with any man, woman or child will no longer be considered as carnal intercourse against the order of nature; it will be considered as normal human sexual behaviour, not an offence punishable under the law.
This new Bill proposes to totally repeal S. 365A of the Penal Code, without any substitution.
S. 365A of the original Penal Code:
‘’Any male person who, in public or private, commits or is a party to the commission of, or procures or attempts to precure the commission by any male person, of any act of gross indecency with another male person shall be guilty of an offence and shall be punished with imprisonment of either description for a term which may extend up to two years or with fine or both, and shall also be liable to be punished with whipping.’’
This provision covered offences committed by male persons only. 1995 Amendment made it applicable to cover offences committed by both male and female persons and made provision for imposing deterrent penalties for offences committed on children.
1995 Amendment of S. 365A of the Penal Code –
‘’Any person who, in public or private, commits or is a party to the commission of, or procures or attempts to precure the commission by any person, of an act of gross indecency with another person is guilty of an offence punishable with imprisonment for a term which may extend up to two years or with fine or both and where the offence is committed by a person over 18 years of age in respect of any person under 16 years of age shall be punished with rigorous imprisonment for a term not less than 10 years and not exceeding 10 years and with fine and shall also be ordered to pay compensation of an amount determined by court to the person in respect of whom the offence was committed for injuries caused to such person.’’
The Supreme Court Determination on the Bill…
Three persons had filed an application – SC SD No. 13 / 2023 – in the Supreme Court challenging the constitutionality of this Bill. Fourteen petitions have been filed by persons seeking Court’s permission to intervene in the Application and the Court has allowed their applications. Out of the 14 intervenient applications, intervenient petitioners only in two applications have supported the petitioners opposing the Bill. Intervenient petitioners in 12 intervenient applications have supported the Bill, opposing the petitioners.
Among the Intervenient petitioners who supported the Bill, there were representatives of four foreign-funded NGOs that have played a leading role in the anti-Sri Lanka campaign carried on in the UN HRC in Geneva making wild allegations against the Govt.
of Sri Lanka since 2006; representatives of 3 or 4 LGBTQ groups; a former Professor in the Faculty of Law, University of Colombo; a leading NGO figure who has served as the President and two other women who have served as members of the Human Rights Commission of Sri Lanka; a women who has served as the President of the National Child Protection Authority; the person who moderated the discussion at the Canadian High Commission and a major activist in the LGBTQ movement in Sri Lanka.
Having examined and analysed the arguments and submissions of the Counsels for the petitioners, intervenient petitioners, respondents and the Attorney General, the Court has made its determination in a lengthy a Judgement. As mentioned in the Judgement:
This Bill proposes to repeal S. 365A in its entirety. ‘‘It must be reiterated that the cumulative effect of the Bill, as captured in Clause (2) (iii), is that sexual orientation of a person shall no longer be a punishable offence, and any consensual conduct between two adult persons of the same sex, irrespective of whether it takes place in private or public, shall no longer be an offence.’’ – P. 10
‘‘The Counsels who appeared for the petitioners opposing the Bill have presented four arguments in support of their position that the provisions of the Bill are violative of Articles 1,3, 4d, 9, 12(1), 13(4), 27(1), 27(2)(d) and 27(13) of the Constitution…It must, perhaps, be stated at the outset that in our view, ex facie, none of the four arguments impinge upon the provisions of Articles 1, 3, 4d, 12(1) and 13(4) of the Constitution….
‘‘The first argument was that the safeguards provided in Ss. 365 and 365A for the protection of children and those under 16 years of age will be taken away by the amendments proposed by the Bill, thereby creating space for exploitation of children and leaving a lacuna in the enforcement of the law relating to offences against children.
‘‘In this connection it was further submitted that:
exposure to lesbian, gay, bisexual and transgender (LGBT) programmes in schools could impact upon the free decision-making power of children and give rise to transgender children;
the enactment of the Bill would be contrary to the provisions in Article 27(13) which provides that ‘The state shall promote with special care the interests of children and youth, so as to ensure their full development, physical, mental, moral, religious and social, and protect them from exploitation and discrimination.’;
the protection presently afforded to children would be removed, if Ss. 365 and 365A are amended as proposed by the Bill, and that even a person under 16 years of age could engage in sexual activity with a person over 18 years of age.
‘‘ It is in this background that this Court was urged as the upper guardian of children to act in the best interests of the child and declare that the Bill is violative of Article 12(1).
The Stand taken by the State…
‘‘The learned Additional Solicitor General Haripriya Jayasundara, PC, submitted that women and children were the focus of the amendments introduced to the PC in 1995, and that while Ss. 365 and 365A were amended by increasing the punishment where one party was a person below the age of sixteen, S. 365B introduced a new offence titled ‘grave sexual abuse.’ It was further submitted by the Additional Solicitor General that the amendment introduced to S, 365B by the Penal Code Amendment Act No. 29 of 1998 specifically provides that consent with regard to any sexual conduct constituting grave sexual abuse is immaterial where the offence is committed in respect of a child below the age of 16. – vide S. 365B(1)(aa). It was her position that in the event the conduct of any person does not fall within the definition contained in S. 365B, S. 345 of the PC which deals with sexual harassment could be resorted to in order to protect children against any unwelcome sexual advances by words or action. Thus, the contention of the petitioners is unfounded and without any legal basis.’’
It appears that the Court has come to this conclusion on the basis of the submission made by the learned Additional Solicitor General. However, her submission is far from correct. It does not appear from the Judgement as to whether the Counsels of the petitioners made any attempt to show the fallacy of the submissions made by the learned ASG.
‘‘The second argument of the Counsels of the petitioners was that the impugned amendment will dilute the Rule of the Law and result in the life and liberty of the citizens being at risk. This argument is even more tenuous and the petitioners have not been able to connect passing of this Bill to any violation of the Rule of the Law.
‘‘The third argument was that a majority of those with HIV and Aids have history of male or bisexual exposure and that decriminalization of same-sex relationships will give rise to an increase in the number of persons infected with HIV and Aids. It was further submitted that this would have an adverse impact on national security by destroying individuals, families, communities, economic and socio-political institutions, and the military police forces, and that the protection granted by the Chapter on fundamental rights cannot be truly enjoyed without the provision of a safe, secure and protective environment in which a citizen of Sri Lanka may realize the full potential of his existence.
‘‘However, little to nothing has been submitted to this court in support of this proposition other than a singular point that HIV and Aids affect those engaging in same-sex intercourse more than those engaging in hetero-sexual intercourse. Hence, the material placed before this Court by the petitioners does not support their position that HIV and Aids are only prevalent in homo-sexuals or that the proposed amendment will result in an increase in the number of persons afflicted with HIV and Aids.
‘‘Counsels for some of the intervenient petitioners presented three important arguments. The first was that it is not only homo-sexual males who contract HIV, but female sex workers, returnee migrant workers and those who use or inject drugs. The second is that criminalization of homo-sexual conduct between two consenting adult males has only resulted in such persons being marginalised from society and thereby being deprived to access of proper health care which if available would address the spread of HIV and Aids among those persons. The third is that the amendment of S. 365 and S, 365A would facilitate the outreach to individuals and groups at a heightened risk of infection. The intervenient petitioners and the ASG agree on the point that the perception that HIV is disproportionately higher in homo-sexuals is due to the social stigma caused by the criminalization of their relationships…..The Counsels of petitioners did not adduce any scientifically acceptable evidence in support of this line of thinking.
The fourth and final argument was that ‘‘homo-sexual activity is contrary to the principles of Buddhism and therefore violates Article 9 of the Constitution…. The petitioners did not explain the manner in which the decriminalization of one’s sexual orientation derogates from the State’s duty protect and foster Buddha Sasana nor the point of how the proposed amendments are prohibited by or contrary to Buddha Sasana, except to state that it is an offence (parajika) for a Buddhist priest to have sexual relations with another, irrespective of whether the other person is of the same sex or opposite sex.
‘‘On the contrary, Mr. Sanjeewa Jayawardana, PC and Mr. Prasantha Lal de Alwis, PC, appearing for some of the intervenient petitioners submitted that: (a) Bhikkus and Bhikkunis have a separate code of conduct (Vinaya rules) and lay persons are not governed by the rules in the said code; (b) none of the ‘sutras’ focussed on the conduct of lay persons condemn homo-sexuality; (c) while the basic tenets of all religions are that all human beings should be treated fairly and equally irrespective of their circumstances, the fundamental teachings of Buddhism includes tolerance towards and equal treatment of all human beings and that Buddhism does not discriminate persons whose sexual orientation is anything other than hetero-sexual; (d) from whatever parity of reasoning, it would be outrageous for the petitioners to allege that a law which decriminalises homosexuality would result in the undermining of the Buddha Sasana.
‘’We are of the view that the final argument of the petitioners too lacks merit.
‘‘Most of the arguments put forward by and in support of the petitioners are largely based on speculation and may be disposed of summarily. For instance, the argument that children would be harmed by the passing of this Bill or the argument that there shall be an increase in the number of those afflicted with HIV and Aids is specious.’’ – P. 17 (To be continued)
Features
‘A remarkable time capsule’: The enchanting history of Oxford University’s 750-year-old medieval library
Predating the Aztec Empire, Merton College Library in Oxford has been used by everyone from celebrated 14th-Century mathematicians to JRR Tolkien. In an exclusive interview with the BBC for its 750th birthday, its librarian describes what makes it so special.
At Merton College in Oxford, there is an antique chest. In the Middle Ages, three key-holders had to be summoned to reveal the riches within. But this treasure wasn’t gold or jewels. It was books.
Such strict security may sound overly cautious for mere parchment. But in an era before the printing press, books were a valuable commodity. They could take months to produce, as the entire text had to be painstakingly written out by hand. So, just as universities solicit cash from their alumni today, Merton College insisted its 13th-Century fellows donated books.
“There’s no single definition of a library” – Prof Teresa Webber
The Archbishop of Canterbury issued a decree in 1276 introducing this requirement, which marked the beginning of the library at Merton College. It has been running continuously ever since. To put that length of time in context, Merton’s library predates the Aztec Empire. Its unbroken history stretches from before the Black Death to beyond the Covid-19 pandemic. And its users have encompassed everyone from famous 14th Century mathematicians to Lord of the Rings author JRR Tolkien.
This month marks the library’s 750th anniversary. It’s a major milestone. But Merton’s extraordinary lifespan has been recognised since the Victoria era, when it was routinely described as the oldest library in England.
In the 20th Century, writers like Rudyard Kipling and John Buchan referenced it in works of historical fiction, bolstering its reputation as a particularly venerable library. As the cultural recognition of “the famous Merton Library” grew, claims about its longevity became exaggerated. Some overzealous Oxonians even declared it the oldest library in the world.
The origins of the historic library
Historians today are more careful about making such bold declarations. “It’s a complicated question,” says Prof Teresa Webber from the University of Cambridge. “There’s no single definition of a library. And there were all sorts of stages in the development of what we think of today as a library.”

The origins of the library at Merton are certainly different from how we think of such institutions now. There was no librarian and there were no shelves for browsing. “There was a system of loaning and returning books from the chest,” Merton’s librarian, Dr Julia Walworth tells the BBC. “It would have been a formal thing. Rather than just saying, ‘Oh, go rummage and find the books you need,’ the whole community would come together to open the chest.”
“Horizontal shelves were installed for placing books upright. Merton is the first recorded use in Britain of this method of storing books” – Dr Julia Walworth
Merton’s collection started evolving into a modern library quite quickly. Just a few years after the Archbishop’s decree, several books were stored outside the chest for the first time. They were chained to a table in the college, making them available at any time. According to Walworth, this innovation “anticipates the modern distinction between loan and reference library collections”.
Merton’s book treasury moved closer to becoming a modern library in the 1370s, when a purpose-built room was constructed to house the growing collection. It was here that Merton introduced a vital improvement in book storage. “Horizontal shelves were installed for placing books upright,” Walworth says. “Merton is the first recorded use in Britain of this method of storing books.”
Curiously, Merton’s books were shelved with their spines inwards and their titles inked on the paper facing out. This was due to the continued use of chains, which were clipped on the fore-edge of each book’s cover. “The fellows were aware that chained books had a better chance of survival than books that went out on loan,” Walworth explains.

Today, just a few volumes in the library are chained – purely for display purposes. And the remaining books are now placed in the modern fashion with their spines out. But otherwise, the medieval room remains a remarkable time capsule of the library’s history. Near the entrance, visitors can even see the 13th-Century chest, which Walworth believes is the original. During term time, the historic library room is still used by students. And this ongoing use is a major factor in the superlatives that are often applied to the age of Merton’s library. “It’s hard to think of an earlier library room that’s been in continuous use,” Webber says.
Claims about Merton’s longevity first gained traction in the Victorian era, as it became more of a tourist destination. Visitors would marvel at its stained-glass windows, as well as rare books like its 15th-Century edition of The Canterbury Tales. “It’s one of the earliest books printed in England,” Walworth explains. “What’s unique about Merton’s copy is the hand-illuminated borders.” Among those who visited the library was American writer Ralph Waldo Emerson, who mentioned it in his 1856 travelogue English Traits. In 1884, a young Beatrix Potter visited, describing the library’s “beautiful oak roof” and “ancient, dusty smell” in her diary.
By this time, books and magazines were increasingly describing the library in record-breaking terms. An 1878 guide to Oxford called Merton’s library “the most ancient now in England”. The 1885 edition of the Encyclopaedia Britannica described it as “the oldest existing library in England”. Gradually, these claims were inflated. A 1928 article in The Times recounted an event held by the Oxford Preservation Trust in which it was declared “the oldest library in the world”.

This growing perception of Merton’s longevity was even referenced in F Scott Fitzgerald’s classic novel The Great Gatsby. In the book, the multi-millionaire title character fills his mansion with imitations of history’s most prestigious rooms. So, it’s only natural that his books live in a recreation he refers to as “the Merton College Library”. As Walworth puts it, “Merton’s library had become a byword for the ‘best’ ancient library” by that time. She even points out that Fitzgerald’s fictional scenario had roots in reality. “The dining clubs at Princeton University have historical imitation rooms. One of them is based on the Merton College Library.”
But today, Walworth rebukes any suggestion that Merton’s library is the world’s oldest. She prefers to describe it with several qualifiers, calling it “one of the oldest still-functioning academic libraries in Europe”. That more measured description recognises that not all historic libraries can be categorised in the same bucket – monastic libraries functioned very differently from private subscription libraries, for instance. But it also acknowledges ancient institutions around the globe. “It’s not that people weren’t aware of other parts of the world in the past,” Walworth says. “But there was a tendency for people to think of their own world as having primacy. Our outlook tends to be more global now, quite rightly.”
The debate over the world’s oldest library
Among these global institutions, there are several candidates for the contested title of world’s oldest library. When the Al-Qarawiyyin library in Morocco underwent a major restoration in 2016, it was described by several media outlets as “the oldest library in the world”. But Guinness World Records cites Saint Catherine’s Monastery in Egypt as the oldest continuously operating library.

In both cases, it’s difficult to establish an exact starting date. For the Al-Qarawiyyin library, some scholars have cast doubt on the library’s claims of Ninth-Century origins, saying the “story has much myth about it”. In the case of Saint Catherine’s Monastery, the building was constructed in the Sixth Century. But ancient writings suggest that the library’s collections could date from two centuries earlier. “It depends how you count it,” Walworth says. “When are you going to start the timeline? What is the beginning of a library?”
However, Prof Richard Gameson from Durham University tells the BBC that the library at Saint Catherine’s Monastery “is probably the one with the longest continuous history”. But he caveats this by adding that “the nature of the ‘library’, how it was used and how it was understood changed over time”. So, any claim to be “the oldest” needs to be accompanied by an appropriate explanation of what a library is. Finding a single definition that allows for one conclusive record-holder seems a near-impossible task.
“You can think of the oldest library as the oldest coherent collection of books that stayed together,” says Webber. “Or you can think of it in terms of the survival of the physical space. Or you could ask, ‘What’s the oldest space and collection of books which has been there continuously?'”
She offers the Dunhuang Library Cave in China as an example. This secret chamber was filled with manuscripts and sealed sometime around the 11th Century. It was only opened again after its rediscovery in 1900. “But the books were still in continuous storage there,” Webber says.

Finding a common definition of a library will only become more challenging now, as digital institutions offer physical spaces that do not even contain any books. “The definition of what a library is has always needed to be a capacious one,” says Webber. “The introduction of new technology is simply a continuation of that. But I don’t think the library as a physical space will disappear.”
Walworth is similarly optimistic, as she embarks on a project to digitise Merton’s manuscripts. “People will be able to access them anywhere. But I think they will still want to come and see the library and understand how people used books in the past.”
Reflecting on the 750-year span of Merton’s library, this digital phase seems like just another step in a long evolution. Just as the books moved from the Archbishop’s chest to chained desks to horizontal shelves, now they will enter the virtual realm. “I suppose that’s why I now find it less useful to talk about libraries as ‘the oldest’,” Walworth says. “For me, the story is not about how long a library has been running. It’s more about the sense of community.”
She points out that the tradition of donating books introduced by the Archbishop of Canterbury in 1276 persists to this day. “What started when he laid down those injunctions was the idea of a common collection built by the people. So, it’s just remarkable that for 750 years people have maintained this connection with an institution and its books.”
Perhaps that proves that books really are the most durable treasure – whether they are handwritten on parchment and sealed in an antique chest or distributed as pixels in the cybernetic ether.
[BBC]
Features
Discovery of molecular structure of primary genetic material of life
World DNA Day falls on 25 April:
On 25 April 1953, Watson and Crick published an article, in the acclaimed journal “Nature” titled “Molecular structure of nucleic acids: A structure for deoxyribonucleic acid”.
The one-page article largely based on theoretical arguments and the previous work of Rosalind Franklin who examined DNA using X-rays, changed the world forever by explaining how genetic information is copied and transmitted.
Everyone concerned with promoting science in the country should be aware of the story behind the discovery of DNA and tell it to their children and students and remind the policymakers.
The world commemorates the transformative event on 25th April every year. An example vividly illustrates how intense curiosity and imagination, rather than mere indulgence in technologies, leads to groundbreaking discoveries.
DNA Day is also intended to celebrate the completion of the Human Genome Project in 2003. Genome means the entire set of genetic information characterising an organism.
Heredity and inheritance
Heredity is the cause of transferring traits from parents to their offspring. The closely related word “inheritance “refers to the specific nature of the transmitted trait. For example, we say intelligence is hereditary in their family and he inherited his father’s intelligence.
The resemblance of progeny to parentage was common knowledge, taken for granted and considered a blending of maternal and paternal traits. Philosophers of antiquity proposed several theories to explain the inheritance of parental traits by the offspring. Hippocrates believed the essence of all body parts of the parents are incorporated into the male and female germinal essence and therefore the offspring display characteristics as a proportionate blend. Aristotle offered a different explanation. He argued that the active principle is in the male seminal fluid and the mother’s blood provided the original body material. The inaccuracy of these theories was apparent. Sometimes children possess qualities akin to grandparents rather than parents. Fathers or mothers of humans and animals, deformed by accidents or disease, gave birth to normal children- a clear proof that the acquired characters are not inherited. Children of a blue-eyed mother and a brown-eyed father have either blue or brown eyes but not a blend of blue and brown.
Two golden sayings in our culture, “Arae gathi nare” and “Jammeta wada lokuei purrudha” (“Hereditary characters persist” and “Habits overtake heredity “), agree more with modern genetics, than the views of Hippocrates and Aristotle.
Gregor Mendal’s groundbreaking experiment
The Austrian mathematician cum botanist, Gregor Mendel was the first to conduct a systematic investigation to understand the cause of heredity. Being unconvinced of the traditional explanations, he carried out a series of experiments lasting eight years to determine how the traits (plant height, seed color, flower color etc.) of pea plants are transmitted from generation to generation. When Mendel cross pollinated tall and short plants, he found that the progeny was entirely tall. However, when first generation tall plants were allowed to self-pollinate, the missing short trait reappeared at a statistically significant probability of 25 percent. Mendel’s work provided an unequivocal proof that traits do not blend but exist as unique entities, manifested from generation to generation following a predictable mathematical pattern.
Mendel’s finding remained unrecognized for more than 30 years. His ideas were too far ahead of time and biologists were shy of mathematics. In the early 1900s several European botanists arrived at the same conclusion based on independent experiments. With the advancement of microscopy, a great deal of information about plant and animal cells was gathered. A key finding was the presence of colored bodies in the cell nucleus named chromosomes, seen separating during cell division, leading to the hypothesis that Mendel’s genetic units (genes) should be physical entities present in the chromosomes.
Chemists and biologists wondered what the genetic material in chromosomes made off. Is it a protein, carbohydrate or a lipid? Most biological materials are constituted of these substances.
Discovery of DNA
Great discoveries are made by unusual people. The Swiss Friedrich Miescher belonged to a clan of reputed physicians. Following family tradition, he qualified as a doctor but did not engage in profitable practice of medicine. He decided to do research to understand the foundations of life. In search for new biological substances, he experimented with pus deposited in bandages and extracted a substance rich in phosphates but very different from proteins. The new substance called “nuclein” was indeed DNA. Later, the German biochemist Albrecht Kossel following the Miescher’s work, showed that DNA contains four crucial compounds, adenine (A), cytosine (C), guanine (G) and thymine (T), known as nucleotide bases.
Avery – MacLeod – McCarthy Experiment
The flu pandemic of 1918 killed an estimated 50 million people worldwide due to the pneumonia that followed the viral infection. Pneumonia was caused by the virulent bacterium Streptococcus pneumoniae. The British bacteriologist, Frederick Griffith attempting to find a vaccine for pneumonia, worked with two strains of Streptococcus pneumoniae, one virulent causing pneumonia in mice, and the other avirulent to them. He found that neither the virulent strain denatured by heating nor the live avirulent strain injected into mice caused the disease, whereas a mixture of the denatured virulent strain and the live avirulent strain was deadly to mice just as the virulent one. He concluded that some chemical compound present in the virulent strain – a transforming principle – has changed the avirulent strain to the virulent strain.
In 1944, Oswald Avery, Colin MacLeod and Maclyn McCarty working at the Rockefeller University, United States, continued the work of Frederick Griffith to identify the transferring principle and found that it is not protein as widely believed, but deoxyribonucleic acid (DNA). Their result pointed to the conclusion that DNA is the carrier of genetic information.
A book by a physicist that triggered a transformation in biology
The insights of brilliant brains engaged in fundamental inquiry have opened the way for major scientific discoveries and technological innovations. In 1944, the Austrian theoretical physicist Erwin Schrodinger, one of the founders of quantum mechanics, published a book titled “What is life? The physical aspect of the living cell “. The American biologist Maurice Wilkins said he was so inspired by Schrodinger’s book and after reading it, he decided to switch from ornithology to genetics. While physicist Maurice was influenced to take up biology. Francis Crick was a physicist working on magnetic mines for the British Admiralty during the war. After reading “What is life” he thought a physicist could find treasures in biology and joined the Cavendish Laboratory in Cambridge to pursue a Ph.D.
Structure of the DNA molecule
When DNA was shown to be the molecular entity that encodes genetic information, chemists rushed to determine its structure.
The pattern formed when X-rays passing through a material cast an image on a screen, provides information about its molecular structure. In 1938, the English physicist William Astbury examined DNA using x-rays and concluded that the molecule has a helical structure. Having heard a group in the United Kingdom was attempting to unearth the structure of DNA, the American theoretical chemist, Linus Pauling, adopted Astbury’s data and proposed a model for the structure of DNA, publishing the results in the journal “Nature” in January 1953.
There was an obscure but remarkably talented person, Rosalind Franklin, pursuing x-ray diffraction studies on DNA at King’s College London. After a painstaking effort, she obtained accurate x-ray diffraction images of DNA. Her colleague, Maurice Wilkins, working in the same laboratory, passed the images to Francis Crick and James Watson at Cavendish Laboratory.
Crick and Watson were more insightful and theoretical in their approach to elucidating the structure of DNA. They, inspired by Erwin Schrodinger’s hypothesis, that the entity accounting for heredity should be an aperiodic molecular entity in cells, arrived at the double helix model, showing that Linus Pauling’s model was erroneous. The Crick – Watson model explained how DNA stores information and replicates during cell division. Their assertions were subsequently confirmed rigorously by experimentation. Crick, Watson and Wilkins received the Nobel Prize for Physiology and Medicine in 1962.
The work following the Crick – Watson model, firmly established that the DNA is a polymer string constituted of two strands made of a sugar- phosphate backbone, connected to each other by linkage nucleotide bases A, T, G, C. The base A links base T and G to C. When one strand is defined by the arrangement of bases, the complementary strand is defined. The arrangement bases store information analogously to a four-letter alphabet. Each individual in a species has a unique sequence of arrangement base pairs. The variation within the species is generally a fraction of a percent.
The Watson-Crick model also explained how the DNA molecule replicates. The two strands unwind and separate, and two complementary strands are inserted. The detailed dynamics of the replication process are not fully understood.
‘DNA is a cookbook’
DNA functions like a multiple – volume cookbook, written in a four-letter alphabet. The volumes are kept in a rack in the kitchen. The rack is the nucleus and volumes on it are the chromosomes, and the cell is the kitchen. A paragraph giving a recipe is a gene. Enzymes act as chefs, who read recipes and give instructions to cell machinery to prepare the dishes, which are proteins. The system is so complex; a complete macroscopic analogy would be impossible.
The significance of the Crick- Watson work
Until Charles Darwin proposed the idea of evolution, biology lacked a theoretical foundation. Darwin hypothesized, when organisms reproduce, the progeny inherit parental characters, but there are variations. The variants, though similar to the parents, have some new or altered characters. If these characters, originating from mutations or cross – breeding are favorable for survival in the environment, they dominate in the population, inheriting advantageous traits. Thus, random generation – to – generation, advancements of living organisms, become possible – a way of improving the design of things in a production process without a designer. Living systems store information and progeny retrieve them, when required. A bird hatched from an egg when matured, knows how to fly.
The discovery of DNA and understanding how it stores genetic information, replicates and mutates explained Darwinian evolution. A mutation is a change in the ordering of base pairs, accidentally during replication or due to external chemical or physical causes. In sexual reproduction, the offspring gets nearly half of its DNA from each parent. Consequently, the offspring does not have DNA identical to one parent. It mixes up DNA in the species. However, mutations generate new genes, driving evolution. Sexual reproduction and mutation acting in concert introduced the diversity of life on earth we see today.
Once science becomes explanatory and predictive, it opens the way for innovations. Theories of mechanics and electromagnetism formulated in the late 19th and early 20th centuries brought forth modern engineering, transforming it from an empirical craft to a scientific technological discipline. Before the discovery of DNA structure and its function, biological innovations were largely empirical. Today we have genetic engineering – genes in organisms can be manipulated. The goal of more advanced genetic engineering, referred to as synthetic biology, aims to induce major genetic changes to organisms by incorporating several genes to alter biochemical, physiological and anatomical functions. Gene technology is rapidly transforming medicine, agriculture and biotechnology. Cures have been found for diseases formerly branded incurable.
How did DNA come into existence
Life is believed to have originated in prebiotic oceans enriched with carbon and nitrogenous substances. How did DNA originate there? Today, chemists can synthesize DNA in minutes, via selective procedures, only humans can do with their knowledge. Even in a vast ocean containing trillions of times more molecular ingredients than in a test tube, a molecule as complex as DNA is most unlikely to be created by random events during the largest possible time scales of the universe. A plausible scenario would be DNA evolving from simpler self-replicating molecules such as RNA (a single strand of DNA) precursors. Unlike RNA, DNA is highly stable and good stability is necessary for the evolution of advanced forms of life.
Epigenetics
Earlier we pointed out there are two golden sayings in our culture: “Arae gathi nare” and “Jammeta wada lokuei purudha (“Hereditary characters persist” and “Habits overtake heredity “). The first is a consequence of our genetic predisposition determined by DNA and explicit genes. However, the character of an individual is also influenced by the physical, social and cultural environment. Although completely non-genetic, our children frequently follow habits we indulge in. Again, the behavior of an individual is also influenced by the physical, social and cultural environment.
The environmental factors also trigger or silence genes. The study of this important genetic effect, which does not alter the sequence of base pairs, is referred to as epigenetics. Epigenetic effects could be deleterious or beneficial. Sometimes, chronic stress causes disease, including cancer. Research suggests engagement in creative and imaginative activities, and establishes favorable epigenetic changes in the brain. Inheritance is dictated mainly by the arrangement of base pairs in DNA. Epigenetic changes involve chemical changes in DNA without altering the sequence. These alterations are erasable but allow transmission to subsequent generations.
Conclusion: World DNA day message to lawmakers
The discovery of the structure of DNA stands as one of the most significant scientific discoveries in human history. It is a lesson to all those involved in research and education, telling how great discoveries originated. It is intense curiosity, imagination and preparation rather than mere indulgence in technologies that clear the path for discovery and innovation. A society that advocates policies conducive to discoveries, also develops new technologies that follow. If we just borrow technologies from places where they originated, hoping for quick economic returns, the effort would be a gross failure. Students, determined to be the best judging from exam performance, engage in professional disciplines and perform exceptionally. Why are we short of discoveries and innovations in those disciplines? Will our lawmakers ever realize the issue? They need to wonder why we are weak in science and poor in innovation. Right policies can even reverse adverse epigenetic attributes propagating in a society!
By Prof. Kirthi Tennakone
ktenna@yahoo.co.uk
National Institute of Fundamental Studies
Features
Death of the Sperm Whale
REVIEWED BY Prof. Rajiva Wijesinha
Earlier this year, I sent her most recent book by an old friend, Kamala Wijeratne. Death of the Sperm Whale is her first book of poetry in four years, though in between she has published fiction, two books though both of them too were slim volumes. I am full of admiration for her in that she keeps going, the last of the poets whom I helped to a wider readership in the eighties, when I championed Sri Lankan writing in English, something hardly any academic was prepared to do in those conservative days.
Kamala’s subjects are those she has explored in the past, but the use of the plural indicates that her range is expansive. She dwells much on nature, but she deals also with political issues, and engages in social criticism. There are several poems about Gaza, the multiple horrors occurring there having clearly affected her deeply. She repeatedly draws attention to the slaughter of children, the infants sent by God only to be taken back. And she deals with the destruction of the life of a doctor, after his healing, a theme that has kept recurring in the ghastly world which is subject to the whims of the incredibly nasty Netanyahu.
The title poem is about a whale destroyed by ingesting plastic, a tragedy to which we all contribute, though those who ‘loll on the beach, their senses dulled by the burgers they eat’ could not care less. More immediate is the simple account of a friend whose infant had died in hospital, when they diagnosed pneumonia too late.
Contrasting with these urgent statements are Kamala’s gentle perceptions, as when she writes of her son supporting her as she walks, while she thinks back to the days she supported him; of a marigold growing in a crack in a shrine, offering obeisance with its golden flowers to the Noble One; of birds investigating her dining room and deciding not to build there, the male lingering ‘confused and irritated’ but eventually following the female through the window for ‘She was mistress after all.’
She is deeply interested in the passing of time, and its impact on our perceptions. The first poem in the book is called ‘First Poem of 2024’ when she ‘heard the weeping of the dying year’, and went on to meditate on how we have categorised the passing of time, while the universe moves on regardless.
She welcomes the return of the Avichchiya, the Indian Pitta, a bird that has figured previously in her poetry, after six months, but this time she spares a thought for his case against the peacock, which stole his plumes.
There are two personal poems, one about a former student who turned her back on her when she had achieved success, the other about being nominated for a literary award, but not getting it after the excitement of attending the Awards Ceremony. Swallowing her disappointment, she congratulates the winner, noting that she will not go into ecstasies the next time she is nominated.
Paraphrase cannot do justice to Kamala Wijeratne’s gentle touch, which has expanded its reach over the years. So,A I will end by quoting from her tribute to Punyakante Wijenaike, another of the distinguished ladies whose work I promoted, the one before the last to leave us. The tribute ends, recalling her most impressive work Giraya,
Like the nutcracker
That makes a clean cut
You cut the human psyche
To reveal its darkest depths
by Kamala Wijeratne
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