Features
Quality of medicinal drugs
by Geewananda Gunawardana Ph.D.
It is a relief to see that some actions are being taken to safeguard the nation’s medicinal drugs supply. Marking the World Antimicrobial Resistance Week, Health Minister Dr. Nalinda Jayatissa stated that laws and regulations governing medicinal drugs must be strengthened. Seeing what has happened to the country’s drug supply in the recent past, that may come as an understatement. The half a billion-dollar question is whether the new administration will be effective in changing the system even if it has good intentions and political muscle. There are a few reg flags raised already. The reason for that doubt is that this problem is shrouded in mystery, presumed to be a subject that we mortals could not understand, a subject only accessible to a certain class of elite. This information gap makes finding a solution to this problem several orders of magnitudes harder than that for many other problems facing the country.
Our problems are not new. In the late nineteenth century, when a shrewd businessman started selling bottled stream water as a panacea, the American authorities saw the need for verifying and regulating medicinal products. That was the beginning of the US Food and Drug Administration. For better or for worse, the infamous human immunoglobulin fiasco when senior officials were caught passing bottled water has triggered Sri Lanka’s FDA moment. We had a system in place, but as the no confidence vote in the parliament highlighted, it had been callously disregarded with impunity for decades. This is not limited to the health sector but deep rooted in all institutions. The continued adoration of the main culprit after the fact shows our ingrained tendency to venerate the elite blindly no matter what harm they inflict. Change has arrived, but success is not guaranteed; we the public must continue to be vigilant.
Vulnerability of systems
The recent incident in which a crook swindled passports right in front of the junior minister highlights the vulnerability of our systems, the gaping information gap, and the extent of disregard for law and order. If a lawmaker can be blinded to a simple protocol, hoodwinking even a well-meaning expert in the field can be child’s play when it comes to drug safety. The process is so convoluted that the proverbial entering through one ear and coming out the other can be extended to any other pore. The decades of neglect and corruption in drug regulation necessitate an all-out war against the system; applying band-aids here and there will not work. Eliminating the information gap is a major step in that process.
There are three main functional areas of specialization involved in getting safe medications to the patients: discovery and development of a drug, diagnosis of the ailment and prescription of the drug, and dispensing the drug to the patient in the prescribed manner. The professionals involved are pharmaceutics experts, medical doctors, and pharmacists. Except in research settings that exist in drug discovery and development organizations, the interactions between the three disciplines stated above are limited. The most common exchange of information takes place through the salespeople of the drug manufacturers; there is no need to explain whose interest they have in mind. As a result, there exists an information gap. Many tend to take it for granted that the world’s drug supply is safe and efficacious; in fact, to the dismay of this writer, a person in a responsible position made a statement to that effect, recently. That would have been true in an ideal world.
The World Health Organization report (2017) estimates that 1 in 10 medicines in low- and middle-income countries are substandard or falsified, and the losses incurred as a result is about $ 30.5 billion annually. According to another report (jamanetworkopen.2018.1685), the figures are higher: 13% substandard drugs and $200 billion in economic losses. No numbers are available for Sri Lanka, but the name of a former health minister should be sufficient to highlight the enormity of the problem, which is reprehensible by any human standards, to say the least.
It is obvious why the substandard drug manufactures target low-income countries and countries with corrupt systems: they are easy targets. We Sri Lankans have more reasons to be vigilant as there are vultures within the system hellbent on looting public funds with impunity and are ready and willing to collude with them. However, there are two powerful tested and proven approaches to curb all these evils. They are Quality Assurance (QA) and Quality Control (QC). If properly administered, they do not leave any room for corruption within this process. However, the irregularities associated with purchasing practices must be dealt with separately.
The scientists that discover, develop, and bring drugs to market identify a set of qualities or attributes of drugs that must be maintained for them to be safe and efficacious. These requirements are known as specifications, and they include a list of tests to be performed on each drug, the analytical test procedures, and appropriate acceptance criteria, which are numerical limits, ranges, or other criteria for the tests described. All such information for all approved drugs is available through the drug manufacturers, approving agencies of the region, and international organizations such as WHO and the International Council for Harmonization (ICH). Following such guidance, these qualities of the drugs and any external factors that may affect them must be monitored and controlled throughout the life of the drug.
Two vital stages
This is done in two stages: quality assurance involves having all necessary precautions in place during manufacture, packaging, storage, distribution, and throughout the shelf life at the pharmacy and the patient’s home. Fortunately, the WHO has a programme for certifying manufacturers and suppliers that meet these stringent requirements. Any drug purchased must be accompanied by a certificate of analysis (CoA), which lists the required qualities, and the test results relevant to that specific lot of drugs. If the drug originates from a WHO certified manufacturer, the CoA is a document that can be trusted. Naturally, having such quality assurance measures is costly, and their products could be more expensive than those coming from uncertified manufacturers. The certificates of analyses originating from non-certified manufacturers require verification by the purchasing country. The verification process becomes much more difficult with injectables and vaccines. The quality control of ‘biologics’ requires special techniques. This is how the low-income countries get in trouble, by going for the least expensive suppliers of drugs.
Even under the best of conditions, things can go wrong, and subpar drugs can enter the system unintentionally. The objective of quality control, the second measure, is to assure that the manufactured product meets all the specifications throughout its life. Therefore, incorporation of a full-fledged quality control function to the system is necessary for ensuring the safety and efficacy of the drugs provided to the patient, not just when it leaves the manufacturing facility. Testing drug samples during the supplier selection process is a necessary step. However, an often-overlooked aspect of this practice is that the samples provided by non-certified manufacturers may not represent the bulk product supplied to the end users. Therefore, periodic testing of drugs circulating through the system is necessary to assure their quality.
Quality control involves performing a set of tests according to the specification set forth by the drug manufacturer in agreement with the approving regulatory agency of the region or country. These tests are various spectroscopic methods to test drug purity, potency, identity, and other critical characteristics. Once the drug is released by the manufacturer, the quality control function goes to the pharmacist, not the doctor nor the pharmaceutics scientist.
The quality control activity must be conducted in accordance with the current Good Manufacturing Practices (cGMP) as described by international agencies like the ICH. An important feature of cGMP is that when implemented properly, it ensures data integrity, traceability, verifiability, and accountability. Almost all the test methods prescribed in specifications are now instrument based. There are hardly any wet chemistries involved as used in pharmacy practice at the turn of the century. As a result, the entire process can be digitalised. That is the system change we need to eliminate corruption. That is the way to bring in desperately needed transparency and accountability.
If the reader gets the impression that what was discussed above are new concepts to the Sri Lankan scene, they are mistaken. Hundreds, if not thousands, of laboratories in many countries are performing these tasks routinely safeguarding their drug supply. They manage to catch inadvertent manufacturing errors and prevent costly and damaging outcomes in a timely fashion. What went wrong in our country?
Bibile and Kottegoda
We have had concerned and forward-looking people like Professors Bibile and Kottegoda and many others who foresaw what was to come. It may come as a surprise, but all the laws and regulations that are necessary to assure the safety and efficacy of drugs exist in the books – the country’s rules and regulations. The facilities, people, and procedures are in place. However, things didn’t go as they expected. According to news reports, there is a shortage of pharmacists in the country. The agency’s labs are not only poorly equipped, but the existing equipment is inadequate and outdated. The agency has become a non-entity; if the fake immunoglobulin samples were tested for identity at a minimum, for example, the debacle that ensued could have been averted.
We must hold all three branches of the government responsible for the erosion of this institution; they have not done their job. They are expected to be independent bodies providing checks and balances. Somewhere along the way, they all got together and colluded to hoodwink us, the people. The situation we are in is no accident: besides the rampant corruption, Sri Lanka did not have a formal academic programme to train pharmacists until recently. Initial efforts to start pharmacy programmes were opposed by the medical profession. Why? Because they viewed it as a threat to their hierarchy in the system. The agency’s laboratories were not maintained at adequate levels because the politicians saw it as an impediment to their nefarious activities. Let us have no illusions that our government, all three branches, were responsible for creating the national ecosystem that made cGMP in state-owned organisations a complete mockery. We the people are responsible as well; after elections, we pay no attention to governance till the next election. If they throw some bones at us, we let them do what they wish. Ignorance reigns throughout.
Fortunately, things have changed favourably. The judiciary liberated itself from the political grip, people cleaned up the rotten politics as best they could. The new President has sent a stern signal that things will be different. He did not send his beloved mother to Singapore for treatment at taxpayer’s expense as previous rulers did. What else is missing? The role of one and a half million civil servants of the country. They have an enormous responsibility at this critical juncture not to let the word bureaucracy become another dirty word like the elite. They are the men and women, our relatives, friends, and colleagues who carry out the day-to-day business of the government. They are expected to be experts in their respective fields and perform their duties according to standard operating procedures without any political bias. The president or the 225 members of the parliament alone cannot run the country no matter how well-meaning their intentions are.
Power of people to make change
We the people have the power to replace the president and the members of the parliament, but we cannot hire or fire bureaucrats. Our system is such that they enjoy lifelong employment regardless of their performance. They get promoted and their pay increases automatically irrespective of their performance. This lack of responsibility is not sustainable. In addition, we must recognize the fact that due to our entrenched practice of political favoritism, some positions were filled with people who are not qualified to carry out their duties. That is not acceptable in any place, but in the drug safety business, which is a recipe for disaster. Therefore, we must recognize the administration’s right to retrain or replace those who do not meet their job descriptions, irrespective of their political affiliations, for the good of the country. That may be unpleasant, but that is the reality.
We must plan for building this expertise in the country. Pharmacy education in our universities must be expanded to include the pharmaceutics functions, especially the analytical aspects. The opportunity exists for the local manufacture of most widely used drugs. That will need expertise on many subjects at various levels. We must develop a culture that encourages innovation; there are many unmet needs as well as opportunities in this field. For example, there is the opportunity to bring Ayurvedic practices to the twenty-first century and add value. Health care is one of the largest industries consuming about 10% of the GDP of most developed countries.
There is no argument that we must procure our drugs from the most affordable sources. However, it must be kept in mind that they are less expensive due to cost-cutting measures taken by the manufacturers, and that could have implications for quality. Therefore, it is paramount that we maintain the integrity of the quality control functions at our end to assure the safety and efficacy of the drugs made available to the patients. This is especially important with the intravenous drugs as there is no room for error; once the drug is injected, there is no way to take it back. Investing in qualified personnel, training, and upgrading the agency’s testing capabilities could be negligible compared to the waste of funds spent on subpar drugs and the suffering they cause.
Features
Silence of the majority keeps West Asian conflict raging
With no military quick-fix in sight to the ongoing, convoluted West Asian conflict it ought to be clear to the rationally inclined that there is no other way to a solution to the blood-letting other than through a negotiated one. Unfortunately, there are not many takers the world over for such an approach.
Consequently the war rages on incurring the gravest human costs to all relevant sides. Whereas it should be obvious to the Trump administration that Iran wouldn’t be backing down any time soon from its position of taking on the US frontally and with the required military competence in the Hormuz Strait and adjacent regions, the US demonstrates a stubbornness to persist with war strategies that are showing no quick, positive results on the ground.
Clearly, the virtual ‘lock down within a lock down’ situation in the Strait is not proving beneficial for either party. Instead, the spilling of civilian blood in particular continues with unsettling regularity along with an all-encompassing economic crisis that carries a staggering material toll for ordinary people all over the world.
From this viewpoint it is commendable for Pakistan to offer itself as a peace mediator and go ‘the extra mile’ to keep the principal parties engaged in some sort of negotiatory process. But its efforts need to win greater support from the world community. It is a time for peace-makers the world over to stand up and be counted.
It is also a time for straight-talking. To his glowing credit Pope Leo XIV is doing just that and he is the only religious head worldwide to do so. Very rightly he has called on President Trump to end the war through negotiations and described it as ‘unjust’ and ‘a scandal to humanity’.
May this crucial cause be taken up by more and more world leaders, is this columnist’s wish. Instead of speaking fatalistically about a ‘Third World War’, decision and policy makers and commentators, and these are found in plenty in Sri Lanka as well, would do better to help in drumming-up support for a peaceful solution and the latter is within the realms of the possible.
Incidentally, the commonplace definition of the phrase ‘World War’ is quite contentious and it would be premature to speak forebodingly about one right now. The fissures within the West on the Middle East conflict alone rule out the possibility of a ‘World War’ occurring any time soon.
Instead, it would be preferable for the international community, under the aegis of the UN, to take the ‘straight and narrow’ path to a peaceful solution. As implied, this path is no easy avenue; it is cluttered with obstacles that only doughty peace makers could take on and clear.
However, the path to a negotiated peace is worth taking and no less a power than the US should know this. After all, the US ‘bled white’ in Vietnam and had to bow out of the conflict, realizing the futility of pursuing a military solution. A similar lesson should have been learned by Russia which bled futilely in Afghanistan. It too is in an unwinnable situation in Ukraine.
The Pope’s observations to President Trump on negotiating peace have earned for him some snarls and growls of criticism but with time these critics would realize that peace could come only by peaceful means and not through ‘the barrel of a gun.’
For far too long the ‘silent majority’ of the world has allowed politicians to take the sole initiative on working towards peaceful solutions to conflicts and wars. As could be seen, the results have been disastrous. The majority of politicians speak the language of Realpolitik only and this tendency runs contrary to the ways of the selfless peace maker.
Power, which is the essence of Realpolitik, and peace are generally at loggerheads in the real world. Power and self-aggrandizement have to be shelved in the pursuit of durable peace anywhere and it is a pity that the likes of Donald Trump and his team are yet to realize this.
At this juncture the ‘peace constituency’ or the silent majority would need to take centre stage and play their rightful role as the ‘Conscience of the World’. If the latter begins to take on the cause of peace in earnest everywhere, the politicians would have no choice but to pay heed to their cause and take it up, since a contrary course would earn for them public displeasure and votes.
An immediate challenge would be for the ‘peace constituency’ to come together and act as one. Right now, such a coordinating role could be played effectively by only the UN and its agencies. Practical problems are likely to get in the way but these need to be managed insightfully and resourcefully by all stakeholders to peace.
In fact the time couldn’t be more appropriate for the backers of peace to come together and work as one. Right now, economic pressures are increasing worldwide and no less a public than that in the US is beginning to feel them in a major, crushing way.
Going ahead the US public, along with other polities, would find the economic consequences of war to be intolerable. There would be no choice but for governments and peoples to champion peace. Peace makers would need to ‘strike while the iron is hot.’
The success of the above endeavours hinges on the importance humans attach to their consciences. The danger about prolonged wars is that they deaden consciences; particularly those of politicians. The latter deaden their consciences to the extent that they prove impervious to the pain and suffering wars incur.
Thus, the ‘peace constituency’ has its work cut out; it cannot rest assured that politicians would prove sensitive to their demands. The latter would need to be constantly dinned into the hearts and minds of politicians and decision-makers if peaceful solutions to conflicts are to be arrived at.
Likewise, the publics of war-torn countries would need to demand the activation and sustaining of accountability processes with regard to those sections that are suspected of committing war crimes and like atrocities. Those publics that cease to demand accountability from powerful sections among them which are faced with war-time atrocity charges are as good as condemning themselves to lives of permanent dis-empowerment and enslavement.
Features
Don’t take the baby: In the quiet night, mother always returns

Chaminda Jayasekara
There is a particular stillness in Sri Lanka’s forests, after dusk — a kind of hushed expectancy where shadows lengthen, cicadas soften their chorus, and the night begins to breathe in its own rhythm. It is a world that does not reveal itself easily. You have to wait for it. You have to listen.
And then, suddenly, you see them — a pair of luminous, unblinking eyes suspended in the dark.
The Grey Slender Loris, or unahapuluwa, emerges, not with drama, but with quiet precision. Small, slow-moving, and almost impossibly delicate, it is one of Sri Lanka’s most enigmatic nocturnal primates — a creature that has survived millennia by mastering the art of stillness.
Yet, during these months — from late March through July — the forests hold a more tender story. It is the breeding season of the slender loris, and with it comes a scene that is often misunderstood by those who encounter it for the first time: a tiny infant, alone on a branch, barely three inches long, its fragile body silhouetted against the night.

Grey Slender Loris with twin babies
To many, it appears to be a moment of abandonment.
To nature, it is a moment of trust.
“People often act out of compassion, but without understanding what they are seeing,” explains Chaminda Jayasekara of the University of Hertfordshire. “A baby loris left alone is not necessarily in danger. In fact, it is part of a natural process that is critical for its survival.”
According to Jayasekara, when a baby loris is about a month old, the mother begins a remarkable routine. As darkness settles, she gently places her infant on a secure branch and moves off into the forest to forage. Her journey can take her hundreds of metres away — sometimes close to 800 metres — as she searches for insects and other small prey.
In those hours of solitude, the infant is not abandoned. It is learning.
Clinging to the branch, it begins to explore its immediate surroundings. Tentatively, almost hesitantly, it reaches out — testing balance, grip, and instinct. It may attempt to catch tiny insects, mimicking behaviours it will one day rely on entirely. This is its first classroom, and the forest its only teacher.
“Those early nights are crucial,” Jayasekara says. “The baby is developing motor skills, coordination, and the ability to interact with its environment. These are things that cannot be replicated in captivity.”
And yet, this is precisely where human intervention often disrupts the process.
Across rural and even semi-urban Sri Lanka, stories circulate of well-meaning individuals who come across a lone baby loris and assume the worst. Driven by concern, they pick it up, take it home, or attempt to hand-rear it — believing they are saving a life.

Grey Slender Loris
But the reality is far more complex — and far more tragic.
“When a baby is removed unnecessarily, it loses something fundamental,” Jayasekara emphasises. “It loses the chance to learn how to survive in the wild. Without that, even if it survives in the short term, its long-term prospects are extremely poor.”
The forest, after all, is not just a habitat. It is a living, evolving system of lessons — how to detect predators, how to navigate branches, how to hunt silently, how to recognise territory. These are not instincts alone; they are behaviours refined through experience.
And the mother, contrary to assumption, is rarely far away.
“If people simply waited — even for several hours — they would often see the mother return,” Jayasekara explains. “She knows exactly where she left her baby. Her absence is temporary, purposeful.”
The advice from conservationists is clear and consistent: observe, but do not interfere.
If you encounter a baby loris, watch quietly from a distance. Avoid using bright lights or making noise. Give it time — at least 10 to 12 hours — before drawing conclusions. In most cases, the situation will resolve itself, just as nature intended.

35 days old Grey Slender Loris
Only if the animal is clearly injured, or if there is strong evidence of abandonment after prolonged observation, should intervention be considered — and even then, it must be done through the proper channels, particularly the Department of Wildlife Conservation.
Attempting to care for such a delicate animal at home is not only ineffective but often fatal.
Sri Lanka is home to two species of slender loris — the Grey Slender Loris and the Red Slender Loris — each adapted to specific ecological zones across the island. Both are protected under national legislation and recognised internationally as species requiring urgent conservation attention.
Their threats are many: habitat loss, road mortality, illegal pet trade, and, increasingly, human misunderstanding.
Yet, in the midst of these challenges, there are also signs of hope.

In recent years, the slender loris has become the focus of a unique form of wildlife tourism — one that values patience over spectacle. Night walks, conducted with trained naturalists and strict ethical guidelines, offer visitors a chance to witness the loris in its natural environment without disturbing its behaviour.
At places like Jetwing Vil Uyana, this approach has been refined into a model of responsible eco-tourism. Over more than a decade, the property has developed a dedicated Loris Conservation Project, recording thousands of sightings while educating visitors and supporting local communities.
Here, the loris is not handled, chased, or exploited. It is simply observed — a quiet presence in a carefully protected landscape.
“The success of such initiatives shows that conservation and tourism do not have to be at odds,” Jayasekara reflects. “When done responsibly, tourism can actually support conservation by creating awareness and value for these species.”
There is something profoundly moving about encountering a loris in the wild. It does not roar or charge. It does not demand attention. Instead, it exists — quietly, deliberately — as it has for millions of years.
And perhaps that is why it is so easily misunderstood.

In a world that often equates visibility with importance, the loris reminds us that some of the most extraordinary lives unfold beyond the spotlight.
It also reminds us of something else — something simpler, yet harder to practice.
Restraint.
Because conservation is not always about stepping in. Sometimes, it is about stepping back. About recognising when nature does not need our help, but our patience.
So if, on some future night, you find yourself walking beneath the trees, and your light catches a tiny figure sitting alone on a branch — do not rush forward.
Pause.
Watch.
Let the moment unfold.
Because somewhere, moving silently through the darkness, guided by instinct and memory, a mother is already on her way back.
And by morning, the forest will be whole again.
By Ifham Nizam
Features
Kumar de Silva: 40 years of fame and flair
We first saw him on the small screen in January 1986 – a relatively raw, totally untrained and a very nervous 24-year-old presenting ‘Bonsoir’ on ITN.
And now, 40 years later, and as one looks back, one realises what a multi-dimensional journey Kumar de Silva has navigated across the small screen yes, from your television screens to your laptops, and iPads, tabs, and mobile phones.
Says Kumar: “It is the French language I speak that opened the world of television to me, 40 years ago. It was ‘Bonsoir’ alone, and so to my French teacher at Wesley College, Mrs. BA Fernando, to ‘Bonsoir’, and to the Embassy of France in Sri Lanka, I am eternally grateful”.

Promoting the French language, and culture, in Sri Lanka, in a big way
Kumar went on to say that on the heels of ‘Bonsoir” came ‘Fanclub’, on ITN, describing it as yet another resounding success story which saw him as a music DJ on TV.
His inherent talent saw him handle a range of contrasting programmes across ITN, TNL, Prime TV and SLRC with consummate ease – from News Reading, Business Talk Shows, Celebrity Chats, to Dhamma discussions, on Poya Days, to name a few.

Kumar – the 1986 look
Trained in Paris in television production and presentation, the Government of France, in 2012, conferred on him the title of ‘Chevalier dans l’Ordre des Arts et Lettres’ (Chevalier in the Order of Arts and Letters) in recognition of his contribution to promoting the French language, and culture, in Sri Lanka.
In celebration of his four decades on the small screen, Kumar recently launched ‘Bonsoir Katha’, the Sinhala translation (by Ciara Mendis) of his English book ‘Bonsoir Diaries’ (2013), at a gala soiree. at the Alliance Francaise de Colombo, under the distinguished patronage of the French Ambassador in Sri Lanka, Remi Lambert, and francophone President Chandrika Kumaratunga.
He’s now excited about launching the French version of this book, ‘Les Coulisses de Bonsoir’, in Paris, in autumn this year. It is currently being translated by Guilhem Beugnon, a former Deputy Director of the Alliance Francaise de Colombo. This will, co-incidentally, also be Kumar’s 30th visit to Paris.

Chief Guest French Ambassador in Sri
Lanka Remi Lambert
Says Kumar: “The word GRATITUDE means a lot to me and so I always make it a point to spend time with two very special French people every time I go to France. One is Madame Josiane Thureau, formerly of the French Foreign Ministry, who began ‘Bonsoir’ in Sri Lanka. way back in the mid-1980s. The other is Madame Aline Berengier, the lady who designed the ‘Bonsoir’ logo – the Sri Lankan elephant in the colours of the French national flag”.
Kumar is also a much-sought-after Personal Development and Corporate Etiquette Coach in Colombo’s corporate world. Over the past 15 years, tens of thousands of corporates, have been through the different modules of his interactive training sessions. There have also been thousands of school leavers and undergraduates from national and private universities, many of whom will constitute the corporates of tomorrow.

Guest of Honour francophone President Chandrika Kumaratunga at the gala soiree
at the Alliance Francaise de Colombo
The multi-talented Kumar turns 65 next year, and his journey on the small screen still continues – you see him on the (monthly) ‘Rendez-Vous with Yasmin and Kumar’ on the French Embassy’s YouTube Channel, and (every Friday) on ‘Fame Game with Rozanne and Kumar’ on Daily Mirror Online, Hi Online and The Sun Online.
There’s yet another podcast in the pipeline, he indicated, but diplomatically declined to give us details. All he said, with a glint in his eye, was, “It will hit your screens soon.”
Whatever he has in mind, one can be certain that the new programme will continue to showcase Kumar de Silva’s enduring presence in Sri Lanka’s entertainment scene.
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