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Fuel crisis has affected fight against dengue,  Neelika tells Nature

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Attempts by Sri Lankan scientists to identify biomarkers that can help determine whether a person has been afflicted with severe dengue have been affected by fuel shortages and power cuts, Immunologist Prof Neelika Malavige told the publication Nature recently.Pro. Malavige said that while most people with dengue had mild disease, and around 15% of people who arrive at hospitals developed dengue haemorrhagic fever, which causes severe bleeding and can be fatal.

“There is no way we can predict at the early stages of an infection whether someone will develop severe dengue, which means that people have to visit the hospital daily for blood tests and monitoring to pick up the signs as early as possible. That’s a huge strain on the health-care system. We are trying to identify biomarkers that can help determine if someone will go on to develop severe dengue. We are also trying to determine the immune response associated with protection from severe disease, which is still unknown for dengue,” she told Nature.

Prof Malavige said that her lab is also looking for drugs that can be repurposed to treat dengue — for which there is no safe and effective vaccine — and has completed several clinical trials.

“We are recruiting and collecting samples for a study with a group in Latin America to compare the epidemiology and pathogenesis of dengue in the two regions. At the same time, we are trying to sequence and isolate the dengue virus to understand what is driving the current outbreak,” she said.

Prof Malavige said that the fuel crisis faced by Sri Lanka was affecting her research as well scientists and researchers in general.

“There are a lot of things we are not doing that we could have done last year. Recruiting participants and collecting samples from the hospital, which is 16 kilometres from our lab, is especially difficult right now because of the lack of fuel. A lot of people have started cycling to/from work, including myself, but cycling between 8 a.m. and 4 p.m. in temperatures above 33 °C, with 80–90% humidity, under the scorching Sun, is a nightmare,” she said.

Excerpts of Prof. Malavige’s interview with Nature: “The power cuts and lack of fuel for back-up electricity generators mean that we cannot use equipment such as our Illumina genomic-sequencing machine, which needs to run continuously for at least 24 hours. Instead, we rely on nanopore sequencing, which can run on a powerful battery. Nanopore sequencing is easier and cheaper and gives better coverage, but has slightly lower accuracy rates. Last week, we managed to sequence a few samples of SARS-CoV-2, because cases have slowly started to rise this month.

“Due to the foreign-reserve crisis, we cannot buy reagents for some of our dengue experiments, so we are freezing many samples for when we can get the reagents. But in March, we had power cuts lasting for up to 13 hours, so we lost samples stored in some of our freezers.

“Some procedures, such as flow cytometry, have to be done on fresh samples, so we have to work around the planned power cuts and restricted opening hours at the university to conduct those experiments. It’s very challenging. I spend most of my time troubleshooting.

“Inflation has driven up the price of many essential lab items. For example, a bottle of the cell-culture medium we use was 4,000 Sri Lankan rupees (US$11 at current conversion rates) in 2021, and is now 36,000 rupees. I’m still just scratching my head trying to figure out how to solve this problem. Can we get the medium at a cheaper rate from manufacturers in China? Immune cells are very sensitive, so they might not grow as well in the new medium.

Our staff are also severely affected by the rising food prices. An egg now costs 50 rupees, up from 17 in 2020. The price of rice, lentils and coconut oil has also shot up. My research assistants and PhD students are really struggling to make ends meet.”



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Prison officers urge Justice Minister to protect their colleague who opened fire

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Coffins of prison staff killed in Monday's clashes at the Negombo Prison, placed at Prison headquarters, Welikada (pic by Nishan S. Priyantha)

Prison officers yesterday requested Justice and National Integration Minister Harshana Nanayakkara to protect their colleague who opened fire at the Negombo Prison during Monday’s riot.

They made that request when the Minister visited the Welikada Prison to pay his last respects to seven officers killed by inmates during the clashes. Soon thereafter, the National Hospital reported that another prison officer had succumbed to his injuries.

The Minister was told that the officer had opened fire through a small opening in the main door to prevent the rioting prisoners from escaping.

The Opposition has demanded to know who ordered the prisons officer to fire. The concerned officer’s colleagues told the Minister that had a breakout occurred the inmates would have posed a serious threat to the public.

Altogether, authorities transferred 1,033 inmates from Negombo to other prisons. Among them was Katuwellegama Suresh, who is alleged to have spearheaded Sunday’s attack on a group of prisoners that led to the following day’s clashes.

Executive Director of the Committee for Protecting the Rights of Prisons, Attorney-at-Law Senaka Perera told The Island that some of the transferred inmates had been mercilessly assaulted in other prisons.

Sources familiar with the situation at prisons said that they were able to accommodate between 11,000 to 12,000 inmates but over 40,000, both convicted and suspects were held in the country’s prisons. About 30,000 of them are suspects. Due to severe overcrowding, prison management had been compelled to accommodate both the convicts and suspects at the Negombo Remand Prison, sources said, adding that the clashes had erupted between the two groups.

Those who had been convicted were accused by the other group of passing information to the previous prison management resulting in elimination of narcotics and other banned items in the prison, sources said. They went on the offensive after both the administrator and the second-in-command were transferred separately and the authorities ignored the volatile situation and proceeded with routine work on Monday.

Sources said that the authorities were yet to release the exact number of convicts and suspects killed and wounded during clashes between the two groups and with prison staff. According to the Health and Media Ministry the total number of persons admitted to the National Hospital, following the incidents, were 29. Of them, 14 were inmates. The Ministry said that of the 29, 12 were in the intensive care unit.

Prof. Prathiba Mahanamahewa told The Island that the overcrowding of prisons should be carefully examined, taking into consideration that even some innocent people were held in various prisons. Poisons, Opium and Dangerous Drugs (Amendment) Act of No 41 of 2022 was being exploited and misused by law enforcement authorities to frame and arrest people. In terms of this law, those who had been framed couldn’t secure bail from the High Court but had to seek the intervention of the Court of Appeal. The lawyer explained how Section 54 of the Act was being used indiscriminately against people.

According to Mahanamahewa about 80 percent of those suspects held were on narcotic charges.

By Shamindra Ferdinando

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Negombo Prison riot: Ensuring protection of prisoners fundamental responsibility of the state – UN

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Marc-André Franche

Expressing concern over the death of prisoners, both convicts and suspects, as well as correctional officers, the United Nations Resident Coordinator in Sri Lanka, Marc-André Franche has emphasised that ensuring that protection is a fundamental responsibility of the State.

Twenty prisoners and seven correctional officers were killed in clashes on Sunday and Monday. Over 100 received injuries.

Issuing a statement, the United Nations extended its condolences to the families affected by the tragedy and wished a speedy recovery to those injured.

Underscoring prison officials carried out challenging duties in service of the State, and the general public, the UN Resident Coordinator said that their loss was deeply felt. The UN also stressed that inmates who died, or were injured, were under the care and protection of the State, emphasising that both correctional officers and prisoners require greater protection. Ensuring that protection is a fundamental responsibility of the State, he said.

The UN statement highlighted the urgent need for continued investment and reform within Sri Lanka’s prison system.

It pointed to longstanding challenges, including overcrowding, outdated practices and poor conditions in detention facilities, which remain concerns in prison systems both in Sri Lanka and globally.

The UN said Sri Lanka’s engagement with international human rights standards, relating to the treatment, safety and wellbeing of persons deprived of liberty, provides an important framework for addressing these issues.

The United Nations welcomed the establishment of an independent committee to investigate the circumstances surrounding the prison violence and emphasised that the committee’s findings should lead to concrete and lasting improvements in detention conditions.

The UN also reaffirmed its commitment to supporting Sri Lanka through technical cooperation aimed at improving prison security, strengthening detention conditions, and supporting the welfare of correctional personnel.

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Govt. considers banning or restricting social media for children under 16: PM

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Harini Amarasuriya

The government was considering imposing restrictions or a possible ban on social media access for children under 16, Prime Minister Harini Amarasuriya told Parliament yesterday (8).

Responding to a question raised by SJB Gampaha District MP Harshana Rajakaruna, the Prime Minister said discussions with relevant stakeholders were currently underway to assess the impact of social media use on children and explore measures to ensure their safety.

She said the consultations, led by the Ministry of Women and Child Affairs, were focussed on the social, mental and health effects of excessive social media use, digital security concerns and global developments in regulating online platforms.

The Prime Minister said the National Child Protection Authority and the National Childcare and Protection Society were also engaged in discussions on the proposal, while steps were being taken to draft national guidelines on restricting access to social media platforms for children below 16 years.

She added that awareness programmes would also be introduced to safeguard children’s mental and physical wellbeing in an increasingly digital environment.

According to the Prime Minister, several government institutions, including the Ministries of Women and Child Affairs, Education, Higher Education and Vocational Education, Health, Mass Media and Digital Economy, along with the Sri Lanka Police, Department of Probation and Child Care Services and the National Child Protection Authority, were collaborating on the initiative.

The PM said the government, together with World Vision, was implementing a programme aimed at addressing mobile phone addiction among children under 18, which had already shown positive results.

Prime Minister Amarasuriya said the government’s focus was to strike a balance between protecting children from potential online harms and ensuring they benefit from digital opportunities.

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