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Battling a rare brain-eating disease in an Indian state

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This single-celled brain-eating amoeba can enter the nose during swimming [BBC]

On the eve of Onam, the most joyous festival in India’s Kerala state, 45-year-old Sobhana lay shivering in the back of an ambulance, drifting into unconsciousness as her family rushed her to a medical college hospital.

Just days earlier, the Dalit (formerly known as untouchables) woman, who earned her living bottling fruit juices in a village in Malappuram district, had complained of nothing more alarming than dizziness and high blood pressure. Doctors prescribed pills and sent her home. But her condition spiralled with terrifying speed: uneasiness gave way to fever, fever to violent shivers, and on 5 September – the main day of the festival – Sobhana was dead.

The culprit was Naegleria fowleri – commonly known as the brain-eating amoeba – an infection usually contracted through the nose in freshwater and so rare that most doctors never encounter a case in their entire careers. “We were powerless to stop it. We learnt about the disease only after Sobhana’s death,” says Ajitha Kathiradath, a cousin of the victim and a prominent social worker.

In Kerala this year, more than 70 people have been diagnosed and 19 have died from the brain-eating amoeba. Patients have ranged from a three-month-old to a 92-year-old man.

Normally feeding on bacteria in warm freshwater, this single-cell organism causes a near-fatal brain infection, known as primary amoebic meningoencephalitis (PAM). It enters through the nose during swimming and rapidly destroys brain tissue.

Kerala began detecting cases in 2016, just one or two a year, and until recently nearly all were fatal. A new study has found only 488 cases have been reported globally since 1962 – mostly in the US, Pakistan and Australia. And 95% of the victims have died from the disease.

Universal Images Group via Getty Images Naegleria fowleri is an amoeba (one-celled living organism) that lives in soil and warm freshwater, such as lakes, rivers, and hot springs. It is commonly called the brain-eating amoeba because it can cause brain infection when water containing the amoeba rises in the nose. Only about three people in the United States are infected each year, but these infections are usually fatal. (Photo by: CDC/IMAGE POINT FR/BSIP/Universal Images Group via Getty Images)
Naegleria fowleri, or the brain-eating amoeba, lives in lakes, rivers and hot springs [BBC]

But in Kerala, survival appears to be improving: last year there were 39 cases with a 23% fatality rate and this year, nearly 70 cases have been reported with about 24.5% mortality. Doctors say the rise in numbers reflects better detection, thanks to state-of-the-art labs.

“Cases are rising but deaths are falling. Aggressive testing and early diagnosis have improved survival – a strategy unique to Kerala,” said Aravind Reghukumar, head of infectious diseases at the Medical College and Hospital in Thiruvananthapuram, the state’s capital. Early detection allows customised treatment: a drug cocktail of antimicrobials and steroids targeting the amoeba can save lives.

Scientists have identified around 400 species of free-living amoebae, but only six are known to cause disease in humans – including Naegleria fowleri and Acanthamoeba, both of which can infect the brain. In Kerala, public health laboratories can now detect the five major pathogenic types, officials say.

The southern state’s heavy reliance on groundwater and natural water bodies makes it particularly vulnerable, especially as many ponds and wells are polluted. A small cluster of cases last year, for example, was linked to young men vaping boiled cannabis mixed with pond water – a risky practice that underscores how contaminated water can become a conduit for infection.

Kerala has nearly 5.5 million wells and 55,000 ponds – and millions draw their daily water from wells alone. That sheer ubiquity makes it impossible to treat wells or ponds as simple “risk factors” – they are the backbone of life in the state.

“Some infections have occurred in people bathing in ponds, others from swimming pools, and even through nasal rinsing with water which is a religious ritual. Whether in a polluted pond or a well, the risk is real,” says Anish TS, a leading epidemiologist.

Nebula NP This pond is located in Sobhana’s village in Malappuram district. The health department’s notice says swimming and bathing in the pond are prohibited until further notice. A warning sign board, preventing people from entering the pond, placed in front of Pathiriyal Valiya Pond in Thiruvali grama panchayat in Malappuram district following the death of a woman due to Amoebic Meningoencephalitis.
A warning sign at a Kerala pond prohibiting swimming after a woman’s death from amoebic meningoencephalitis [BBC]

So public health authorities have tried to respond at scale: in a single campaign at the end of August, 2.7 million wells were chlorinated.

Local governments have put up sign boards around ponds warning against bathing or swimming and evoked the Public Health Act to enforce regular chlorination of swimming pools and water tanks. But even with such measures, ponds cannot realistically be chlorinated – fish would die – and policing every village water source in a state of more than 30 million people is unworkable.

Officials now stress awareness over prohibition: households are urged to clean tanks and pools, use clean warm water for nasal ablutions, keep children away from garden sprinklers and avoid unsafe ponds. Swimmers are advised to protect their noses by keeping their heads above water, using nose plugs and avoiding stirring up sediment in stagnant or untreated freshwater.

Yet, striking a balance between educating the public about real risks – of using untreated freshwater – and avoiding fear that could disrupt daily life is challenging. Many say despite guidelines issued for more than a year, enforcement remains patchy.

“This is a difficult problem. In some places [hot springs], signs are posted to warn of the possibility of the amoebae in the water source. This is not practical in most situations since the amoebae can be present in any source of untreated water [lakes, ponds, pools],” Dennis Kyle, a professor of infectious diseases and cellular biology at the University of Georgia, told the BBC.

“In more controlled environments, frequent monitoring for proper chlorination can significantly reduce chances of infection. These include pools, splash pads and other man-made recreational water activities,” he said.

Abhishek Chinnappa/Getty Images Boys use a makeshift raft to cross a canal in Kerala.
Kerala has nearly 5.5 million wells and 55,000 ponds [BBC]

Scientists warn climate change is amplifying the risk: warmer waters, longer summers and rising temperatures create ideal conditions for the amoeba. “Even a 1C rise can trigger its spread in Kerala’s tropical climate and water pollution fuels it further by feeding bacteria the amoeba consumes,” says Prof Anish.

Dr Kyle adds a note of caution, noting that some past cases may simply have gone unrecognised, with the amoeba not identified as the cause.

That uncertainty can make treatment even harder. Current drug cocktails are “sub-optimal,” Dr Kyle explains, adding that in rare survivors, the regimen becomes the standard. “We lack sufficient data to determine if all the drugs are actually helpful or needed.”

Kerala may be catching more patients and saving more lives, but the lesson reaches far beyond its borders. Climate change may be rewriting the map of disease – and even the rarest pathogens may not stay rare for long.

[BBC]



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Tensions erupt in Indian state after 11-year-old raped and murdered

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A protest in Kolkata against the rape and murder of the 11-year-old in Baruipur [BBC]

The Indian state of West Bengal has been on the boil for the past few days over the rape and murder of an 11-year-old girl.

The body of the child was fished out from a pond on Sunday – a day after her family reported her missing.

The incident in Surjyapur village in Baruipur, on the outskirts of Kolkata, has triggered days of violent protests, a mob lynching of an innocent man and the police killing of one of the suspects. Three other men who have been arrested remain in custody.

Warning: This story contains details that some readers may find distressing.

The child’s rape and murder – and the subsequent killing of the suspect – has snowballed into a huge political row, with the opposition parties accusing the state’s newly-elected Bharatiya Janata Party (BJP) government of failing to protect women.

PTI Baruipur engulfed in flames after the girl's body was recovered
Baruipur saw violent protests after the girl’s body was found [BBC]

Family members of the girl said they last saw her on Saturday afternoon when she went out to buy a birthday gift for a friend. When she didn’t return home, they went to the police station at around 20:30 to seek help in finding her.

The family and villagers alleged that the police did not take their pleas seriously and said they would look into it the next day.

Desperate family members and villagers then themselves looked through the CCTV footage from nearby shops and spotted her walking with Prabhash Mondal – a local man who has since been killed by the police.

Early Sunday morning, a mob went to Mondal’s house, caught him and handed him over to the police.

A few hours later, a sack containing the girl’s body was pulled out from the pond, with media reports saying Mondal had led the police to the exact spot.

According to the post-mortem report, the cause of death is drowning, leading to claims that she was alive when she was dumped in the pond.

“Had the police acted earlier, she could have been saved,” her relatives have said.

The police complaint has since been amended to include charges under the Pocso, India’s stringent law on child sexual abuse. The police have yet to hold a press conference on the case or respond to the allegations.

The government has formed a special investigation team (SIT) to inquire into the case.

ANI Chief Minister Suvendu Adhikari went to meet the victim's family in Baruipur
Chief Minister Suvendu Adhikari met the victim’s family and assured them of justice [BBC]

The recovery of the body saw anger pour out onto the streets, with a mob vandalising roads, shops and a local railway station. A young man was beaten to death by the crowd – Chief Minister Suvendu Adhikari has since said he was innocent.

Several police officers were injured and vehicles damaged as they tried to contain the mob. Police have registered three cases and detained 40 people so far.

The area remains tense, with a ban on public gatherings and heavy police and paramilitary deployment to maintain order.

The unrest poses a huge challenge for the BJP, which swept to power in West Bengal for the first time ever in May, campaigning heavily on the issue of making the state safe for women.

Analysts say one of the main reasons three-term chief minister Mamata Banerjee lost the election was growing concern over women’s safety and her government’s shoddy handling of the rape and murder of a junior doctor at a government hospital.

This case has also become mired in a political controversy and is threatening to take on religious overtones as the victim was Muslim whereas the arrested men are Hindus.

A local BJP leader, Sushant Mondal’s home was attacked and ransacked by a mob that accused him of helping the suspects. He denied the allegations saying they were “false” and that he had in fact “helped catch the perpetrators”.

To contain the public anger, Chief Minister Suvendu Adhikari visited the village on Tuesday and met the victim’s family.

“Our government is committed to curb any such incidents in the state. The police is doing what needs to be done. The family has spoke to me, they have lost their beloved daughter. I believe that they are satisfied talking to me.”

Less that 24 hours later, Prabhash Mondal was killed in a “police encounter”.

In a statement on Wednesday morning, Baruipur police said Mondal had been taken to the pond to recreate the crime scene as part of the investigation, but he attempted to snatch the weapon from a policeman and opened fire at them. The police retaliated and fired back, striking him. The injured accused was taken to hospital, where he was declared dead, the statement said.

Even though no allegations had been proven against Mondal, his mother appeared to have disowned her son and refused to accept his body.

“Two policemen came to my house. I had just woken up. They told me that my son had died and asked if I wanted to go to the hospital. I told them I couldn’t because my husband was ill,” she told news agency ANI. “I said, do whatever you want to do. I have no objection. My son has been punished for what he did. I will not accept his body. I will not even bring his body home,” she added.

Opposition politicians and rights activists, however, have questioned the killing, saying it went against the rule of law.

Ranjit Sur of the Association for the Protection of Democratic Rights called the matter “suspicious”.  Sur said the story of police encounters in many states of the country is almost the same – the accused tries to escape by snatching the police weapon and is then killed in the encounter.

In 2019 in a similar incident, four men accused of gang-raping and murdering a young woman in Hyderabad were killed by the police in an encounter.

[BBC]

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Canadian PM visits Saudi Arabia to strengthen energy, mining partnerships

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Canada's Mark Carney and Saudi Arabia's Crown Prince Mohammed bin Salman met on the heels of the NATO summit [Aljazeera]

Canadian Prime Minister Mark Carney paid a visit to Saudi Arabia, marking the first state visit in more than a quarter-century as Ottawa and Riyadh explore deeper mining and energy ties.

Carney visited on Thursday, on the heels of the NATO summit in Turkiye, doubling down on calls to diversify trade relationships as United States President Donald Trump imposed tariffs that have weighed on the Canadian economy. The visit included agreements covering mining, energy and artificial intelligence, which Carney’s office said would be finalised next year.

The two countries signed 13 new agreements and memorandums of understanding (MoUs) covering areas including health and defence. The agreements are worth $1bn. Among the deals are agreements that would help Canadian companies develop mining and clean energy projects in Saudi Arabia.

During his visit, Carney also met with Amin Nasser, head of state oil giant Saudi Aramco. On energy, Carney’s office said the two countries are working together on agreements related to liquefied natural gas, hydrogen and carbon capture and storage.

Carney’s office also said he would lead “a delegation of Canada’s pension funds” as part of efforts to invest in Saudi Arabia’s energy and AI sectors.

In talks with Saudi Crown Prince Mohammed bin Salman, Carney signed agreements aimed at expanding several key partnerships between the two nations following years of strained relations under former Prime Minister Justin Trudeau.

Trudeau, Carney’s predecessor, had been critical of Saudi Arabia’s treatment of human rights activists, including Saudi writer Raif Badawi and his sister, Samar. In response, Saudi Arabia expelled the Canadian ambassador and cut trade and investment ties in 2018.

Ottawa and Riyadh began restoring diplomatic ties in 2023.

Carney was asked by reporters about the decision to re-engage with Saudi Arabia, to which he responded:

“Engaging with the country doesn’t mean that we agree with everything that a country is doing.”

“We are actively engaging with key partners around the world,” Carney said.

“Lecturing countries from afar is an ineffective strategy. It’s satisfying, but it’s ineffective.”

Carney was also asked about ongoing negotiations with the United States. Reporters pressed him on whether there had been any progress in trade negotiations with Trump amid tensions surrounding the North American Free Trade Agreement. “I’ll keep you posted,” Carney said.

[Aljazeera]

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Eight killed after landslide hits girls’ school in Bangladesh

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A school at a refugee camp in Cox's Bazar was hit by the landslide (BBC)

Seven students and a teacher have been killed in Bangladesh after a landslide hit a girls’ school inside a refugee camp

The Islamic study centre in the coastal city of Cox’s Bazar was buried by mud and debris on Wednesday afternoon, sparking frantic search and rescue efforts. It is unclear how many people were inside the school.

The country has been battered by monsoon rains since Sunday, with several deadly landslides reported in Cox’s Bazar.

More than one million Rohingya people live there in what is the world’s largest refugee settlement, having fled a deadly military crackdown in Myanmar.

Rescuers pulled 13 people from the mud that engulfed their school hut, eight of whom died, the Refugee Relief and Repatriation Commissioner Mohammed Mizanur Rahman said.

“Some of them are seven, eight, 11 or 12 years old,” Panna Akhter, a local district officer, told BBC Bangla.

The other five children were taken to hospital for treatment.

Rohingya Khobor A large crowd gathers around a muddy site as people work by hand to try to rescue people from under the mud
Crowds gathered at the school to pull out students who had become submerged (BBC)

Earlier, officials said other landslides had killed at least eight Rohingya refugees, including five children, since Sunday.

Thousands of Rohingya, one of Myanmar’s many ethnic minorities, were killed and more than 700,000 fled to neighbouring Bangladesh during an army crackdown in Myanmar in 2017

The group, which is primarily Muslim, are denied citizenship by the government of Myanmar, a Buddhist-majority country.

Many face poor living conditions in Bangladesh, living in makeshift homes of tarpaulin and bamboo on steep hillsides.

More rain is forecast for the coming days, with authorities issuing warnings for more landslides and floods, and evacuating families in high risk areas.

(BBC)

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