News
“Three-in-one blood pressure pill can significantly reduce risk of recurrent strokes”
A major international clinical trial has found that a once-daily, three-in-one blood pressure pill can significantly reduce the risk of recurrent strokes among patients who have survived a brain bleed, or haemorrhagic stroke, Kelaniya University’s media division announced yesterday.
The TRIDENT trial, coordinated in Sri Lanka by a team led by Senior Professor Asita de Silva of the Clinical Trials Unit, Faculty of Medicine, University of Kelaniya, showed that the low-dose combination pill reduced the risk of a repeat stroke by up to 40 per cent and the risk of another brain bleed by 60 per cent among high-risk patients. The findings were published on April 23 in the New England Journal of Medicine.
The pill combines three commonly used antihypertensive medications—amlodipine, telmisartan and indapamide—into a single daily dose. Researchers said the simplified regimen improves patient adherence and supports better blood pressure control, a key factor in preventing further strokes, heart attacks and other cardiovascular complications.
The trial followed 1,670 stroke survivors across 11 countries over a seven-year period, including participants from 11 specialist neurology centres in Sri Lanka. Nearly 73 per cent of participants were Asian, with close to 70 per cent from Sri Lanka, making the findings particularly relevant to the country and the wider South Asian region.
An estimated 60,000 people in Sri Lanka suffer strokes annually, while cardiovascular disease accounts for more than 40 per cent of all deaths. Around 40 per cent of Sri Lankan adults aged 30 to 79 are affected by high blood pressure, the leading risk factor for stroke.
Professor de Silva said a decade of clinical trials involving Sri Lankan and international researchers had consistently shown the effectiveness of a triple low-dose combination therapy in controlling blood pressure. He noted that the drug has recently been approved by the U.S. Food and Drug Administration and included in the World Health Organization’s Model List of Essential Medicines. He described the findings as a “game changer” in reducing recurrent stroke risk through sustained blood pressure control.
He also highlighted Sri Lanka’s significant contribution to the study, noting that nearly 70 per cent of the trial data was generated locally, underscoring the country’s growing role in global medical research.
Dr. Bimsara Senanayake, Specialist Neurologist and Lead Investigator at the National Hospital of Sri Lanka, said the findings address longstanding gaps in the treatment of intracerebral haemorrhage, where effective strategies for intensive blood pressure management have remained uncertain for decades. He noted that improved blood pressure control could substantially reduce the risk of further life-threatening events among survivors.
In a statement, World Stroke Organization President Professor Jeyaraj Pandian described the trial as a major advance in stroke prevention, highlighting the benefits of effective blood pressure management following intracerebral haemorrhage.
The findings are expected to inform changes in clinical practice, particularly as the triple-combination pill used in the trial has already received regulatory approval and global recognition for the treatment of hypertension.
Dr. Ajantha Keshavaraj, President of the Association of Sri Lankan Neurologists and a co-author of the study, said the results could significantly change the management of post-stroke blood pressure, adding that the treatment—combined with lifestyle measures such as reduced salt intake—has the potential to save thousands of lives.
An accompanying editorial in the New England Journal of Medicine also underscored the importance of strict blood pressure control as a priority in preventing cardiovascular disease.
News
US embassy won’t comment on IGP’s probe into joint drug raid
… America-Pakistan developed required ‘intel’ for operation
By Shamindra Ferdinando
The US Embassy in Colombo declined to comment on a special police probe into the recent narcotics detection, jointly made at the China-managed Colombo International Container Terminal (CICT) by the US Drug Enforcement Administration’s (DEA) New Delhi Country Office and Sri Lanka Police..
US Embassy spokesperson said that the mission wouldn’t add to their press release, issued on 2 Sept., in the immediate aftermath of the raid.
Police Headquarters, on 11 Sept., declared that the Central Crime Investigation Bureau (CCIB) was conducting investigations into the recovery of 473 kg of Crystal Methamphetamine (‘Ice’). Police never acknowledged the role played by the US in the operation.
According to Police Headquarters, on a directive given by IGP Priyantha Weerasooriya, the Special Investigation Unit has launched an internal probe into, what it called, shortcomings and irregularities in the Colombo Port raid.
The Island:
Have you (relevant US authorities) received an update of Sri Lanka’s investigations from the Police?
US Embassy:
U.S. and Sri Lankan law enforcement authorities maintain close and ongoing cooperation on counternarcotics matters, including the exchange of information that helps both countries combat transnational drug trafficking. We don’t have anything further to share on communications with Sri Lankan authorities beyond what we’ve already said publicly about the successful operation.
The Island:
Did the Police seek clarification regarding DEA, New Delhi Country Office role in the successful raid?
US Embassy:
As the Embassy noted publicly following the seizure, cooperation with the U.S. Drug Enforcement Administration contributed to the Sri Lanka Police Narcotics Bureau’s successful seizure of approximately 463 kilograms of methamphetamine at the Port of Colombo.
The seizure demonstrates the value of close U.S.-Sri Lankan cooperation in disrupting transnational narcotics trafficking.
The Island:
Before we raised this issue were you aware of the internal investigation into the drug bust which was also raised in Parliament last week?
The US Embassy:
We don’t have anything further to share beyond what we’ve already said publicly about the successful operation.
Our focus remains on the strong U.S.-Sri Lanka law enforcement partnership and the concrete results our cooperation can deliver—disrupting transnational criminal organisations, cutting off the profits that fuel illicit drug trafficking, and protecting our citizens from the dangers of narcotrafficking.
The US Embassy attributed the success of the counternarcotics operation to the US-Sri Lanka partnership
The US Embassy statement, dated 2 Sept: The U.S. Drug Enforcement Administration’s (DEA) New Delhi Country Office and Sri Lanka’s Police Narcotics Bureau (PNB) conducted a successful joint operation disrupting a Pakistan-based narcotrafficking network attempting to smuggle crystal methamphetamine through Sri Lanka to international markets.
Acting on intelligence developed by DEA’s Foreign Counterparts Unit Pakistan Anti-Narcotics Force Special Investigations Cell between August 14–29 on suspicious maritime containers moving from Pakistan to Colombo, PNB seized approximately 463 kg of crystal methamphetamine with a street value of $21 million, concealed in bath towels, and arrested several suspects, including Pakistani nationals. This operation underscores the strength of the U.S.-Sri Lanka partnership in dismantling transnational criminal organisations that fund terrorism and threaten communities in both our countries. This cooperation builds on long-standing training and technical assistance provided through the U.S. Department of State’s Bureau of International Narcotics and Law Enforcement Affairs (INL) to the Sri Lanka Police and Customs. The United States remains committed to working with Sri Lanka and regional partners to aggressively pursue transnational criminal organizations, deny them the revenue from illicit drug trafficking, and protect our citizens from the dangers of narcotrafficking.”
SLPP National Organiser Namal Rajapaksa, in Parliament, raised questions about the internal investigation into the raid. However, Rajapaksa, too, hasn’t mentioned the US role in the operation. The Special Investigation Unit has recorded a statement from Senior DIG Ranmal Kodituwakku regarding the Colombo Port raid.
MP Rajapaksa questioned the rationale behind questioning the officer who led the raid against the backdrop of controversial releasing of 323 containers from the Colombo Port in January 2025. The failure to question those responsible for the releasing of 323 containers indicated who was behind that operation, MP Rajapaksa told Parliament.
News
Gnanasara Thera declares outside High Court that he wouldn’t flee
Bodu Bala Sena (BBS) General Secretary Ven. Galagodaaththe Gnanasara Thera appeared before the Colombo High Court yesterday in a case filed by the Attorney General over statements allegedly insulting Islam.
The case was taken up before Colombo High Court Judge Buddhika C. Ragala, who ordered that it be called again on September 30.
His appearance came six days after the Supreme Court invalidated the presidential pardon granted to Gnanasara Thera by former President Maithripala Sirisena in 2019.
Speaking to journalists outside the court, Gnanasara Thera said he was prepared to face the legal process and would abide by the law, rejecting reports that he had gone into hiding following the Supreme Court judgment.
“It is the weak who disappear and flee. We worked for the country and are facing the consequences for that. We are not afraid and will not flee,” he said, noting that he would surrender to the court and face whatever legal consequences following the Supreme Court decision.
The Supreme Court, on September 10, ruled that the presidential pardon granted to Gnanasara Thera by Sirisena was invalid. The judgment followed fundamental rights petitions challenging the legality of the pardon. A three-judge bench, comprising Justices Janak de Silva, Sobhitha Rajakaruna and Sampath Abeykoon, delivered the ruling.
Gnanasara Thera was convicted by the Court of Appeal in 2018 for contempt of court and sentenced to a total of 19 years’ imprisonment to run concurrently as six years. The conviction related to his conduct during proceedings at the Homagama Magistrate’s Court concerning the disappearance of Prageeth Eknaligoda.
He was released from Welikada Prison on May 23, 2019, after then President Maithripala Sirisena had granted him a presidential pardon.
The Supreme Court found the pardon to be arbitrary and invalid in law, following its consideration of the petitions challenging the exercise of the presidential power of clemency.
Meanwhile, police have said they are awaiting the Supreme Court judgment before determining what further action should be taken following the invalidation of the pardon.
The proceedings before the Colombo High Court yesterday are separate from the contempt of court case that resulted in the six-year sentence. They concern alleged statements made by Gnanasara Thera regarding Islam.
In June this year, the Colombo High Court rejected an appeal by Gnanasara Thera against a nine-month prison sentence imposed by the Colombo Magistrate’s Court in connection with statements made at a 2016 media briefing that were found to have disrupted religious coexistence.
The latest High Court proceedings, therefore, form part of separate legal action concerning his alleged remarks about Islam, while the Supreme Court ruling relates specifically to the legality of the 2019 presidential pardon granted in connection with his contempt of court conviction.
The case before the Colombo High Court will be called again on September 30.
News
Namal further remanded
Colombo Fort Magistrate Pasan Amarasena yesterday (16) ordered SLPP National Organiser Namal Rajapaksa, MP, to be further remanded, until September 23. The Magistrate issued the order when Rajapaksa was produced before the court as a suspect in an investigation into an alleged USD 2 million bribe case connected to the acquisition of aircraft for SriLankan Airlines.
The Magistrate issued the order following the submissions made by Deputy Solicitor General Janaka Bandara, appearing on behalf of the Criminal Investigation Department (CID).
President’s Counsel Anil Silva, along with other attorneys representing Rajapaksa, also made submissions before the court.
The Magistrate also announced that a decision on Rajapaksa’s bail application would be announced on 23 September.
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